Abemaciclib Impurity 155 CAS CATO-C4X-2937155
| CAS No. | CATO-C4X-2937155 |
| Molecular Formula | C27H33FN8 |
| Molecular Weight | 488.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Abemaciclib Impurity 155 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Abemaciclib Impurity 155 (CAS CATO-C4X-2937155) is a certified pharmaceutical impurity reference standard with the molecular formula C27H33FN8 and a molecular weight of 488.60 g/mol.
Abemaciclib Impurity 155 (C27H33FN8) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 155 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H33FN8 |
| Molecular Weight | 488.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib Impurity 156 (CAS CATO-C4X-2937156)
- Abemaciclib Impurity 71 (CAS CATO-C4X-293771)
- Abemaciclib Impurity 72 (CAS CATO-C4X-293772)
- Abemaciclib Impurity 102 (CAS 2704316-81-2)
- Abemaciclib Impurity 178 (CAS 1942029-13-1)
- Abemaciclib Impurity 141 (CAS CATO-C4X-2937141)
- Abemaciclib Impurity 142 (CAS CATO-C4X-2937142)
- Abemaciclib Impurity 136 (CAS CATO-C4X-2937136)
Recommended Standards
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- N-(2-Bromobenzyl)-2-chloro-N-ethylethan-1-amine (CAS 62078-98-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com