Abemaciclib Impurity 158 CAS CATO-C4X-2937158
| CAS No. | CATO-C4X-2937158 |
| Molecular Formula | C12H10N4O3 |
| Molecular Weight | 258.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Abemaciclib Impurity 158 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Abemaciclib Impurity 158 (CAS CATO-C4X-2937158), a pharmacopoeial impurity reference standard (molecular formula C12H10N4O3, MW 258.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Abemaciclib Impurity 158 (C12H10N4O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H10N4O3 |
| Molecular Weight | 258.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Abemaciclib Standards
- Abemaciclib Impurity 147 (CAS 2189739-28-2)
- Abemaciclib Impurity 187 (CAS CATO-C4X-2937187)
- Abemaciclib Impurity 164 (CAS CATO-C4X-2937164)
- Abemaciclib Impurity 49 (CAS CATO-C4X-293749)
- Abemaciclib Impurity N5 (CAS 1038408-36-4)
- Abemaciclib Impurity 35 (CAS CATO-C4X-293735)
- Abemaciclib Impurity 180 (CAS CATO-C4X-2937180)
- Abemaciclib Impurity 100 (CAS 658072-14-1)
Recommended Standards
- Olsalazine EP Impurity C (CAS 259151-72-9)
- Afoxolaner Impurity 10 (CAS CATO-C4X-313710)
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- 5-Methyluridine (CAS 1463-10-1)
- Trazodone Impurity 72 DiHCl (CAS 2408971-27-5)
- Triamcinolone Acetonide Impurity 38 (CAS CATO-C4X-132638)
- Atosiban Impurity 48 (CAS CATO-C4X-229348)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com