Abemaciclib Impurity 179 CAS CATO-C4X-2937179
| CAS No. | CATO-C4X-2937179 |
| Molecular Formula | C39H32O2P2 |
| Molecular Weight | 594.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Abemaciclib Impurity 179.
Abemaciclib Impurity 179 (CAS CATO-C4X-2937179) is a certified pharmaceutical impurity reference standard with the molecular formula C39H32O2P2 and a molecular weight of 594.62 g/mol.
The molecular framework of Abemaciclib Impurity 179 (C39H32O2P2) is characterized by organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Abemaciclib Impurity 179 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C39H32O2P2 |
| Molecular Weight | 594.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Abemaciclib Standards
- Abemaciclib Impurity 90 (CAS CATO-C4X-293790)
- Abemaciclib Impurity 58 (CAS CATO-C4X-293758)
- Abemaciclib impurity 121 (CAS CATO-C4X-2937121)
- Abemaciclib Impurity 19 (CAS CATO-C4X-293719)
- Abemaciclib Impurity 74 (CAS CATO-C4X-293774)
- Abemaciclib Impurity 150 (CAS CATO-C4X-2937150)
- Abemaciclib Impurity 190 (CAS CATO-C4X-2937190)
- Abemaciclib Impurity 143 (CAS CATO-C4X-2937143)
Recommended Standards
- Glutathione Impurity 23 (CAS CATO-C4X-118523)
- 2,2'-(((1S,2S)-2-(((R)-2-(Bis(carboxymethyl)amino)-3-(4-isothiocyanatophenyl)propyl)(carboxymethyl)amino)cyclohexyl)azanediyl)diacetic acid (CAS 157380-45-5)
- (S)-C3-TunePhos (CAS 486429-99-6)
- 2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfonyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (CAS 1863036-51-4)
- Apalutamide Impurity 47 (CAS 1805396-62-6)
- Relugolix Impurity 38 (CAS CATO-C4X-242938)
- Erlotinib Impurity 61 (CAS 20825-87-0)
- n-(2,2-Diethoxyethyl)-3-methylpentan-2-amine (CAS 1506510-00-4)
- 4-Chloro-6-(methylthio)-5-(1H-pyrrol-1-yl)pyrimidine (CAS 1713602-50-6)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- (Hydroxymethyl)triphenylphosphonium (tetrafluoroborate) (CAS 2340-49-0)
- 4-(Cyclohex-2-en-1-ylmethyl)-1H-imidazole (CAS 317337-95-4)
- 2-(2-(Methylthio)phenyl)-5-(prop-2-yn-1-ylthio)-1,3,4-oxadiazole (CAS 339015-34-8)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com