Abemaciclib Impurity 80 CAS CATO-C4X-293780
| CAS No. | CATO-C4X-293780 |
| Molecular Formula | C28H33F2N7O |
| Molecular Weight | 521.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Abemaciclib Impurity 80 (CAS CATO-C4X-293780), a pharmacopoeial impurity reference standard (molecular formula C28H33F2N7O, MW 521.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Abemaciclib Impurity 80 (C28H33F2N7O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Abemaciclib Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H33F2N7O |
| Molecular Weight | 521.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Abemaciclib Standards
- Abemaciclib Impurity 81 (CAS CATO-C4X-293781)
- Abemaciclib Impurity 103 (CAS CATO-C4X-2937103)
- Abemaciclib Impurity 84 (CAS CATO-C4X-293784)
- Abemaciclib Impurity 134 (CAS CATO-C4X-2937134)
- Abemaciclib Impurity 17 (CAS CATO-C4X-293717)
- Abemaciclib Impurity 18 (CAS CATO-C4X-293718)
- Abemaciclib Impurity 25 (CAS CATO-C4X-293725)
- Abemaciclib Impurity 66 (CAS CATO-C4X-293766)
Recommended Standards
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- CAY10573 (CAS 853652-40-1)
- Flurbiprofen Impurity 93 (CAS CATO-C4X-144493)
- Ursodeoxycholic acid impurity 52 (CAS 517-37-3)
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- Methyl 5-(hydroxymethyl)tricyclo[3.3.0.0(3,7)]Octane-1-carboxylate (CAS 2445793-16-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com