Abemaciclib Impurity 103 CAS CATO-C4X-2937103
| CAS No. | CATO-C4X-2937103 |
| Molecular Formula | C27H31F2N8O |
| Molecular Weight | 521.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Abemaciclib Impurity 103 (C27H31F2N8O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Abemaciclib Impurity 103 (CAS CATO-C4X-2937103), a pharmacopoeial impurity reference standard (molecular formula C27H31F2N8O, MW 521.58 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 103 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H31F2N8O |
| Molecular Weight | 521.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib Impurity 80 (CAS CATO-C4X-293780)
- Abemaciclib Impurity 81 (CAS CATO-C4X-293781)
- Abemaciclib Impurity 84 (CAS CATO-C4X-293784)
- Abemaciclib Impurity 137 (CAS CATO-C4X-2937137)
- Abemaciclib Impurity 138 (CAS CATO-C4X-2937138)
- Abemaciclib Impurity 59 (CAS CATO-C4X-293759)
- Abemaciclib Impurity 134 (CAS CATO-C4X-2937134)
- Abemaciclib Impurity 17 (CAS CATO-C4X-293717)
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- 2-Methyl-1-((3-(trifluoromethyl)pyridin-2-yl)oxy)propan-2-amine (CAS 1340143-02-3)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com