Abemaciclib Impurity 86 CAS CATO-C4X-293786
| CAS No. | CATO-C4X-293786 |
| Molecular Formula | C27H32F2N8O |
| Molecular Weight | 522.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Abemaciclib Impurity 86 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 522.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Abemaciclib Impurity 86 (CAS CATO-C4X-293786, C27H32F2N8O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H32F2N8O |
| Molecular Weight | 522.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib Impurity 134 (CAS CATO-C4X-2937134)
- Abemaciclib Impurity 17 (CAS CATO-C4X-293717)
- Abemaciclib Impurity 18 (CAS CATO-C4X-293718)
- Abemaciclib Impurity 25 (CAS CATO-C4X-293725)
- Abemaciclib Impurity 66 (CAS CATO-C4X-293766)
- Abemaciclib Impurity 68 (CAS 2138499-06-4)
- Abemaciclib Impurity 87 (CAS CATO-C4X-293787)
- Abemaciclib Impurity 84 (CAS CATO-C4X-293784)
Recommended Standards
- β-Casomorphin (1-4) (bovine) (CAS 74171-19-0)
- Z-Asn(Mtt)-OH (CAS 144317-18-0)
- Z-Gln(Trt)-OH (CAS 132388-60-4)
- 4,4'-(6,6'-Bis(pyridin-3-ylmethoxy)-[1,1'-biphenyl]-3,3'-diyl)dipyridine (CAS 1388182-17-9)
- Carbocisteine Impurity 49 (CAS 907565-13-3)
- Vortioxetine Impurity 87 (CAS 34570-17-7)
- Betamethasone impurity 72 (CAS CATO-C4X-143772)
- 5-(4-Chlorophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 380906-28-5)
- 5-Bromo-2-methylquinolin-8-ol (CAS 24263-94-3)
- 4-(4-Fluoro-3-(trifluoromethyl)phenyl)picolinonitrile (CAS 1219454-49-5)
- Dihydrotestosterone Heptanoate (CAS 33776-88-4)
- Azilsartan Impurity 127 (CAS CATO-C4X-1096127)
- (3-Bromoisoxazol-5-yl)methanamine (CAS 2763-93-1)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com