Abemaciclib Impurity 87 CAS CATO-C4X-293787
| CAS No. | CATO-C4X-293787 |
| Molecular Formula | C27H32F2N8O |
| Molecular Weight | 522.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Abemaciclib Impurity 87 (C27H32F2N8O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Abemaciclib Impurity 87 (CAS CATO-C4X-293787, C27H32F2N8O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abemaciclib Impurity 87 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H32F2N8O |
| Molecular Weight | 522.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib Impurity 134 (CAS CATO-C4X-2937134)
- Abemaciclib Impurity 17 (CAS CATO-C4X-293717)
- Abemaciclib Impurity 18 (CAS CATO-C4X-293718)
- Abemaciclib Impurity 25 (CAS CATO-C4X-293725)
- Abemaciclib Impurity 66 (CAS CATO-C4X-293766)
- Abemaciclib Impurity 68 (CAS 2138499-06-4)
- Abemaciclib Impurity 86 (CAS CATO-C4X-293786)
- Abemaciclib Impurity 84 (CAS CATO-C4X-293784)
Recommended Standards
- β-Casomorphin (1-4) (bovine) (CAS 74171-19-0)
- Z-Asn(Mtt)-OH (CAS 144317-18-0)
- Z-Gln(Trt)-OH (CAS 132388-60-4)
- 4,4'-(6,6'-Bis(pyridin-3-ylmethoxy)-[1,1'-biphenyl]-3,3'-diyl)dipyridine (CAS 1388182-17-9)
- Alectinib Impurity 92 (CAS CATO-C4X-283692)
- Carfilzomib Impurity 91 (CAS CATO-C4X-102291)
- Cyclophosphamide Impurity 22 (CAS 3308-51-8)
- Diflubenzuron (CAS 35367-38-5)
- N-((5-(4-Nitrophenyl)-1H-1,2,4-triazol-3-yl)methyl)aniline (CAS 1171664-52-0)
- 3-Ethoxy-4-[(6-nitro-4H-1,3-benzodioxin-8-yl)methoxy]benzaldehyde (CAS 554438-66-3)
- 4-Bromo-1H-pyrrolo[3,2-c]pyridin-3-amine (CAS 1190317-68-0)
- 2-Chloro-4-(trifluoromethyl)oxazole (CAS 1060816-15-0)
- Methyl (R)-3-amino-2,3-dihydro-1H-indene-5-carboxylate (CAS 1212974-29-2)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com