Abemaciclib Impurity 9 CAS CATO-C4X-29379
| CAS No. | CATO-C4X-29379 |
| Molecular Formula | C24H36N6O |
| Molecular Weight | 424.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Abemaciclib Impurity 9.
As a process- or degradation-related impurity, Abemaciclib Impurity 9 (CAS CATO-C4X-29379, C24H36N6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Abemaciclib Impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 424.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H36N6O |
| Molecular Weight | 424.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Abemaciclib Standards
- Abemaciclib Impurity 34 (CAS CATO-C4X-293734)
- Abemaciclib Impurity 10 (CAS CATO-C4X-293710)
- Abemaciclib Impurity 75 (CAS CATO-C4X-293775)
- Abemaciclib Impurity 51 (CAS CATO-C4X-293751)
- Abemaciclib Impurity 188 (CAS CATO-C4X-2937188)
- Abemaciclib Impurity 189 (CAS CATO-C4X-2937189)
- Abemaciclib Impurity 41 (CAS CATO-C4X-293741)
- Abemaciclib Impurity 145 (CAS CATO-C4X-2937145)
Recommended Standards
- Repaglinide Impurity 22 (CAS CATO-C4X-118622)
- 3-(4-Benzylpiperidin-1-yl)-1-(7-methoxy-2,3-dihydrobenzo[f][1,4]thiazepin-4(5H)-yl)propan-1-one (CAS 145903-06-6)
- 4-(4-Ethyl-5-(isopropylthio)-4H-1,2,4-triazol-3-yl)-1-((4-methoxyphenyl)sulfonyl)piperidine (CAS 672950-65-1)
- 2-Bromo-6-[(1E)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}methyl]-4-methoxyphenol (CAS 477848-03-6)
- Doxorubicin Impurity N19 (CAS 106401-68-7)
- Dipyridamole EP Impurity C (CAS 54093-92-4)
- Racecadotril EP Impurity B (CAS 76721-89-6)
- tert-Butyl (2-((5-bromo-2-nitrophenyl)amino)ethyl)carbamate (CAS 1071527-72-4)
- 3-[(3-Fluorobenzyl)oxy]azetidine (CAS 1121634-60-3)
- 3-Isopropyl-2-heptanone (CAS 6972-54-9)
- Ethyl 3-amino-4-(butylamino)benzoate (CAS 1220018-22-3)
- N-Methyl-1-(1-methyl-1H-1,2,4-triazol-3-yl)methanamine (CAS 215871-45-7)
- 4-((3-(o-Tolyl)-1,2,4-oxadiazol-5-yl)methoxy)benzaldehyde (CAS 1120293-37-9)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com