Acalabrutinib Impurity 25 CAS CATO-C4X-305525

Purity 95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-305525
Molecular FormulaC14H15N5O
Molecular Weight269.30 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Acalabrutinib Impurity 25 CAS CATO-C4X-305525 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Acalabrutinib Impurity 25 (CAS CATO-C4X-305525) is a certified pharmaceutical impurity reference standard with the molecular formula C14H15N5O and a molecular weight of 269.30 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Acalabrutinib Impurity 25 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 269.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H15N5O
Molecular Weight269.30 g/mol
Purity95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms5

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