Ribociclib Impurity 18 CAS CATO-C4X-310018
| CAS No. | CATO-C4X-310018 |
| Molecular Formula | C12H15N3O2 |
| Molecular Weight | 233.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ribociclib Impurity 18 (CAS CATO-C4X-310018) is a certified pharmaceutical impurity reference standard with the molecular formula C12H15N3O2 and a molecular weight of 233.27 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Ribociclib Impurity 18 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ribociclib Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15N3O2 |
| Molecular Weight | 233.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Ribociclib Standards
- Ribociclib Impurity 22 (CAS CATO-C4X-310022)
- Ribociclib Impurity 36 (CAS 2387711-02-4)
- Ribociclib Impurity 33 (CAS CATO-C4X-310033)
- Ribociclib Impurity 15 (CAS CATO-C4X-310015)
- Ribociclib impurity 39 (CAS 2304957-86-4)
- Ribociclib Impurity 14 (CAS 1331847-17-6)
- Ribociclib Impurity 28 (CAS CATO-C4X-310028)
- Ribociclib Impurity 14 (CAS CATO-C4X-310014)
Recommended Standards
- Belumosudil Impurity 65 (CAS CATO-C4X-298865)
- Vazegepant Impurity 1 (CAS CATO-C4X-32001)
- Tegoprazan Impurity 140 (CAS CATO-C4X-2297140)
- 2,2':6',2''-Terpyridine (CAS 1148-79-4)
- Lasmiditan Impurity 1 (CAS 79538-29-7)
- Dirithromycin EP Impurity D(Dirithromycin C) (CAS CATO-C4X-14284)
- Relugolix Impurity 73 (CAS CATO-C4X-242973)
- Mecoprop-n/isobutyl ester (CAS CATO-CCPD102116)
- Poly(oxy-1,2-ethanediyl), α-(2-aminoethyl)-ω-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]- (CAS 1207751-12-9)
- N,N-Dimethyl-3-azepanamine (CAS 933733-52-9)
- (S)-6,6'-Bis([1,1'-biphenyl]-4-yl)-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol (CAS 1258327-00-2)
- 1-(1-ethyl-1H-pyrazol-4-yl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 1153208-26-4)
- 5-Methoxy-1H-pyrrolo[2,3-c]pyridin-2(3H)-one (CAS 878483-98-8)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
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