Ribociclib impurity 2 CAS CATO-C4X-31002
| CAS No. | CATO-C4X-31002 |
| Molecular Formula | C23H29N9O2 |
| Molecular Weight | 463.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ribociclib impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Ribociclib impurity 2 (CAS CATO-C4X-31002), a pharmacopoeial impurity reference standard (molecular formula C23H29N9O2, MW 463.54 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ribociclib impurity 2 (C23H29N9O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H29N9O2 |
| Molecular Weight | 463.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 9 |
Related Ribociclib Standards
- Ribociclib Impurity 10 (CAS CATO-C4X-310010)
- Ribociclib Impurity 9 (CAS 2460732-08-3)
- Ribociclib Impurity 25 (CAS CATO-C4X-310025)
- Ribociclib Impurity 23 (CAS CATO-C4X-310023)
- Ribociclib Impurity 19 (CAS CATO-C4X-310019)
- Ribociclib Impurity N1 (CAS 2069953-39-3)
- Ribociclib Impurity 17 (CAS 2514753-27-4)
- Ribociclib Impurity 24 (CAS CATO-C4X-310024)
Recommended Standards
- o-Toluoyl-5-hydroxy Omeprazole Sulfide (CAS 120003-78-3)
- (3R,5S,E)-Propyl 7-(2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl)-3,5-dihydroxyhept-6-enoate (CAS 917752-49-9)
- [Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-methanone (CAS 1392443-41-2)
- Boc-Aminooxy-PEG4-Tos (CAS 1807539-01-0)
- Ceftolozane impurity 4 (CAS 1956303-56-2)
- Ataluren Impurity 7 (CAS 775303-92-9)
- Valaciclovir EP Impurity D(hydrochloride) (CAS 1346617-49-9)
- 1-(Hexyloxy)-4-iodobenzene (CAS 85557-94-4)
- Arotinolol Impurity 16 (CAS CATO-C4X-185416)
- 4-[(4-Nitrophenoxy)methyl]piperidine hydrochloride (CAS 1220029-57-1)
- gamma-D-Glutamylaminomethylsulfonic acid (CAS 90237-02-8)
- Dotinurad Impurity 32 (CAS CATO-C4X-249432)
- Amphotericin B EP Impurity C (CAS CATO-C4X-18444)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com