Encorafenib Impurity 3 CAS CATO-C4X-32493
| CAS No. | CATO-C4X-32493 |
| Molecular Formula | C20H25ClFN7O2S |
| Molecular Weight | 481.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Encorafenib Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Encorafenib Impurity 3 (CAS CATO-C4X-32493) is a certified pharmaceutical impurity reference standard with the molecular formula C20H25ClFN7O2S and a molecular weight of 481.97 g/mol.
Encorafenib Impurity 3 (C20H25ClFN7O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H25ClFN7O2S |
| Molecular Weight | 481.97 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Encorafenib Standards
- Encorafenib Impurity 11 (CAS CATO-C4X-32411)
- Encorafenib Impurity 10 (CAS 1269440-78-9)
- Encorafenib Impurity 18 (CAS CATO-C4X-324918)
- Encorafenib Impurity 13 (CAS CATO-C4X-324913)
- Encorafenib Impurity 15 (CAS CATO-C4X-324915)
- Encorafenib Impurity 9 (CAS CATO-C4X-32499)
- Encorafenib Impurity 12 (CAS CATO-C4X-324912)
- Encorafenib Impurity 8 (CAS CATO-C4X-32498)
Recommended Standards
- Amlodipine Impurity 41 (CAS 331258-31-2)
- 2-(Benzylsulfanyl)-3-[(3-chloro-4-methoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroquinazolin-4-imine (CAS 477848-72-9)
- (T-4)-[3-Bromo-5-[(4-bromo-3,5-dimethyl-2H-pyrrol-2-ylidene-κN)phenylmethyl]-2,4-dimethyl-1H-pyrrolato-κN]difluoroboron (CAS 910823-84-6)
- 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-((3-methoxybenzyl)thio)quinazolin-4(3H)-imine (CAS 860610-63-5)
- Midecamycin Impurity 20 (CAS CATO-C4X-312220)
- Bupropion Impurity 16 (CAS 76650-08-3)
- Mavacamten Impurity 9 (CAS 67463-81-4)
- Diethylenetriamine (CAS 111-40-0)
- 2-Methyl-5-oxododecan-2-yl oxazole-4-carboxylate (CAS 86838-83-7)
- 3-iodo-1H-pyrrolo[2,3-β]pyridine (CAS 23616-57-1)
- 3-Azido-7-hydroxycoumarin (CAS 817638-68-9)
- 5-Chloro-1H-indol-1-amine (CAS 119229-70-8)
- 2-Octyldodecanal (CAS 13893-37-3)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com