Aprocitentan Impurity 4 CAS CATO-C4X-33554
| CAS No. | CATO-C4X-33554 |
| Molecular Formula | C16H13Br2N7O5S |
| Molecular Weight | 575.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Aprocitentan Impurity 4 (CAS CATO-C4X-33554), a pharmacopoeial impurity reference standard (molecular formula C16H13Br2N7O5S, MW 575.19 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution, Aprocitentan Impurity 4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 575.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Aprocitentan Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13Br2N7O5S |
| Molecular Weight | 575.19 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Aprocitentan Standards
- Aprocitentan Impurity 5 (CAS CATO-C4X-33555)
- Aprocitentan-d4 (CAS CATO-C4X-335510)
- Aprocitentan impurity 2 (CAS CATO-C4X-33552)
- Aprocitentan Impurity 8 (CAS CATO-C4X-33558)
- Aprocitentan Impurity 6 (CAS CATO-C4X-33556)
- Aprocitentan Impurity 7 (CAS CATO-C4X-33557)
- Aprocitentan Impurity 9 (CAS CATO-C4X-33559)
- Aprocitentan impurity 3 (CAS CATO-C4X-33553)
Recommended Standards
- Magnesium Phthalocyanine (CAS 1661-03-6)
- (E)-{[1-(4-chlorophenyl)-4-[(4-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indol-5-yl]methylidene}amino benzoate (CAS 477887-82-4)
- Bis(p-octyloxybenzylidene) 2-chloro-1,4-phenylenediamine (CAS 26456-28-0)
- Gadoteridol Impurity 50 (CAS CATO-C4X-225750)
- Atorvastatin Impurity 150 (CAS 676260-66-5)
- Lercanidipine Impurity 65 (CAS CATO-C4X-136465)
- Butenafine Impurity 5 (CAS 101828-08-4)
- 2-Bromo-6-methoxy-4-{[(2-methylpropyl)amino]methyl}phenol hydrochloride (CAS 1240567-59-2)
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- S-(2-(N-((4-Amino-2-methylpyrimidin-5-yl)methyl)formamido)-5-(phosphonooxy)pent-2-en-3-yl) 3-phenylprop-2-enethioate (CAS 751-21-3)
- 2-(1-methylpiperazin-2-yl)ethan-1-ol (CAS 889939-92-8)
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- 4-Cyano-6-(difluoromethyl)-2-methoxypyridine-3-methanol (CAS 1806950-38-8)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
Why CATO?
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