Aprocitentan impurity 2 CAS CATO-C4X-33552
| CAS No. | CATO-C4X-33552 |
| Molecular Formula | C16H13Br2N5O5S |
| Molecular Weight | 547.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 547.18 g/mol gives Aprocitentan impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Aprocitentan impurity 2 (CAS CATO-C4X-33552) is a certified pharmaceutical impurity reference standard with the molecular formula C16H13Br2N5O5S and a molecular weight of 547.18 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution, Aprocitentan impurity 2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 547.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Aprocitentan impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13Br2N5O5S |
| Molecular Weight | 547.18 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Aprocitentan Standards
- Aprocitentan-d4 (CAS CATO-C4X-335510)
- Aprocitentan Impurity 4 (CAS CATO-C4X-33554)
- Aprocitentan Impurity 5 (CAS CATO-C4X-33555)
- Aprocitentan Impurity 8 (CAS CATO-C4X-33558)
- Aprocitentan Impurity 6 (CAS CATO-C4X-33556)
- Aprocitentan Impurity 7 (CAS CATO-C4X-33557)
- Aprocitentan Impurity 9 (CAS CATO-C4X-33559)
- Aprocitentan impurity 1 (CAS CATO-C4X-33551)
Recommended Standards
- Boc-3,5-diiodo-Tyr-OMe (CAS 128781-80-6)
- Dotinurad Impurity 18 (CAS CATO-C4X-249418)
- 3-{4-[(2-chlorophenyl)methyl]-5-oxo-4h,5h-[1,2,4]triazolo[4,3-a]quinazolin-1-yl}-N-(2-{[(furan-2-yl)methyl](propan-2-yl)amino}ethyl)propanamide (CAS 902965-92-8)
- (4'-Bromo-[1,1'-biphenyl]-4-yl)(hydroxy)-lambda3-iodanyl 4-methylbenzenesulfonate (CAS 919474-55-8)
- Ruxolitinib Impurity 14 (CAS CATO-C4X-2058114)
- Methotrexate Impurity 72 (CAS CATO-C4X-115472)
- Lapatinib Impurity 3 (CAS 59404-86-3)
- Camsirubicin (CAS 236095-26-4)
- 4-Bromo-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-methanol (CAS 1804464-89-8)
- Dimethyl 5-aminocyclohexane-1,3-dicarboxylate (CAS 313683-57-7)
- 4-(3-bromothiophen-2-yl)-N-methylpyrimidin-2-amine (CAS 1516757-44-0)
- Albendazole sulfone-d3 (CAS 1448345-60-5)
- 3-(2,2-Dimethoxyethoxy)phenylboronic acid (CAS 1256355-35-7)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com