Tivozanib Impurity 24 CAS CATO-C4X-340024
| CAS No. | CATO-C4X-340024 |
| Molecular Formula | C19H17ClN2O4 |
| Molecular Weight | 372.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Tivozanib Impurity 24 (CAS CATO-C4X-340024) is a certified pharmaceutical impurity reference standard with the molecular formula C19H17ClN2O4 and a molecular weight of 372.80 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tivozanib Impurity 24 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H17ClN2O4 |
| Molecular Weight | 372.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tivozanib Standards
- Tivozanib Impurity 28 (CAS CATO-C4X-340028)
- Tivozanib Impurity 7 (CAS CATO-C4X-34007)
- Tivozanib Impurity 2 (CAS CATO-C4X-34002)
- Tivozanib Impurity 5 (CAS CATO-C4X-34005)
- Tivozanib Impurity 29 (CAS CATO-C4X-340029)
- Tivozanib Impurity 3 (CAS CATO-C4X-34003)
- Tivozanib Impurity 26 (CAS CATO-C4X-340026)
- Tivozanib Impurity 19 (CAS CATO-C4X-340019)
Recommended Standards
- Oxametacin (CAS 27035-30-9)
- Quizalofop-Ethyl (CAS 76578-14-8)
- N,N-DI-BOC-2-CHLORO-4-NITROANILINE (CAS 252019-65-1)
- Quizalofop-P-Ethyl (CAS 100646-51-3)
- Glutamic acid Impurity 2 (CAS 51865-66-8)
- Atrasentan Impurity 13 (CAS 1063836-08-7)
- Epalrestat Impurity 27 (CAS CATO-C4X-223627)
- 2-[3-(4-chlorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]acetic acid (CAS 70751-12-1)
- (E)-2-propenoic acid, 3-cyclopropyl-2-methyl-, ethyl ester (CAS 21014-30-2)
- 5-Bromo-6-methoxy-1,3-dihydro-2-benzofuran (CAS 1781444-68-5)
- 2-(4-(2,2-Dicyanovinyl)-2-methoxyphenoxy)-N-phenylacetamide (CAS 333341-47-2)
- 5,7-Dichlorothiazolo[4,5-d]pyrimidine (CAS 1137278-39-7)
- Ethyl 2,4,6-tribromo-3-hydroxybenzoate (CAS 773128-79-3)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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