Tivozanib Impurity 7 CAS CATO-C4X-34007
| CAS No. | CATO-C4X-34007 |
| Molecular Formula | C18H17ClN2O4 |
| Molecular Weight | 360.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Tivozanib Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Tivozanib Impurity 7 (CAS CATO-C4X-34007, C18H17ClN2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tivozanib Impurity 7 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN2O4 |
| Molecular Weight | 360.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tivozanib Standards
- Tivozanib Impurity 2 (CAS CATO-C4X-34002)
- Tivozanib Impurity 24 (CAS CATO-C4X-340024)
- Tivozanib Impurity 28 (CAS CATO-C4X-340028)
- Tivozanib Impurity 5 (CAS CATO-C4X-34005)
- Tivozanib Impurity 29 (CAS CATO-C4X-340029)
- Tivozanib Impurity 3 (CAS CATO-C4X-34003)
- Tivozanib Impurity 17 (CAS CATO-C4X-340017)
- Tivozanib Impurity 4 (CAS CATO-C4X-34004)
Recommended Standards
- Tolvaptan Impurity 13 (CAS CATO-C4X-195513)
- (E)-N-{7-[1-(4-chloro-2-methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N'-methoxymethanimidamide (CAS 477865-59-1)
- Methyl (3E)-3-{[(4-chlorophenyl)methoxy]imino}-2-(phenylformamido)propanoate (CAS 318284-58-1)
- 4-(4-Chlorophenyl)-1-{5H-pyrimido[5,4-b]indol-4-yl}-1H-pyrazol-3-amine (CAS 318469-18-0)
- Posaconazole Impurity 18(R,S,S,R) (CAS 213381-06-7)
- Silodosin Impurity 30 (CAS 1639265-45-4)
- Abiraterone Impurity N6 (CAS 853-23-6)
- 2-((m-Tolyloxy)methyl)-1,3-dioxolane (CAS 850348-74-2)
- Ethyl 4-hydroxy-2-morpholinopyrimidine-5-carboxylate (CAS 25693-41-8)
- Boc-D-Val-OH (CAS 22838-58-0)
- 2-(Methoxymethyl)-1-methylpiperazine (CAS 734507-92-7)
- 2-((5-(Pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanol (CAS 604740-89-8)
- (E)-2-Isopropyl-5-methyl-2-hexenal (CAS 69104-96-7)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com