Methotrexate Diethyl Ester CAS CATO-CIM-105887
| CAS No. | CATO-CIM-105887 |
| Molecular Formula | C24H30N8O5 |
| Molecular Weight | 510.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Methotrexate Diethyl Ester (CAS CATO-CIM-105887), a certified reference material (molecular formula C24H30N8O5, MW 510.55 g/mol) for analytical method development and quality control.
Methotrexate Diethyl Ester (C24H30N8O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Methotrexate Diethyl Ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H30N8O5 |
| Molecular Weight | 510.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Methotrexate Standards
- Methotrexate Diethyl Ester (CAS 43170-88-3)
- Methotrexate impurity 52 (CAS CATO-C4X-115452)
- Methotrexate Dimethylamide Sodium Salt (CAS CATO-C4X-115436)
- Methotrexate impurity 51 (CAS CATO-C4X-115451)
- Methotrexate-d (CAS 432545-60-3)
- Methotrexate Impurity 83 (CAS CATO-C4X-115483)
- Methotrexate impurity 50 (CAS CATO-C4X-115450)
- Methotrexate impurity 53 (CAS CATO-C4X-115453)
Recommended Standards
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(2-methyl-5-nitrophenyl)acetamide (CAS 332018-82-3)
- Ethyl 5-(2-{[6-tert-butyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamido)-4-cyano-3-methylthiophene-2-carboxylate (CAS 625377-43-7)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(3-nitrophenyl)propanamide (CAS 332101-02-7)
- Cyclohexyl 2-(3,4,5-trifluorophenyl)ethyl ketone (CAS 898778-77-3)
- 4-Methanesulfonyl-1-methoxy-2-nitrobenzene (CAS 20945-69-1)
- 1-(4-Bromo-2-fluorophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1016697-56-5)
- 5-(4-Chloro-2-methylphenoxymethyl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 748793-44-4)
- 6-(Chloromethyl)pyridine-2,4-dicarbaldehyde (CAS 1393550-18-9)
- 2,6-Dimethoxy-4-pyrimidinecarbonyl chloride (CAS 52759-24-7)
- N-((3-Methyl-1,2,4-oxadiazol-5-yl)methyl)-2-phenyl-2H-tetrazole-5-carboxamide (CAS 1396795-10-0)
- 7-((Tert-butoxycarbonyl)(methyl)amino)-5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 2271470-66-5)
- Posaconazole Impurity 281 (CAS CATO-C4X-1208281)
- 3-Amino-6-bromo-2,4-dichloropyridine (CAS 237435-16-4)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com