Ticagrelor Impurity 153 CAS CATO-C4X-1093153
| CAS No. | CATO-C4X-1093153 |
| Molecular Formula | C7H10ClN3S |
| Molecular Weight | 203.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ticagrelor Impurity 153.
As a process- or degradation-related impurity, Ticagrelor Impurity 153 (CAS CATO-C4X-1093153, C7H10ClN3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ticagrelor Impurity 153 (C7H10ClN3S) contains a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 203.69 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 153 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10ClN3S |
| Molecular Weight | 203.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 74 (CAS 220352-36-3)
- Ticagrelor impurity 136 (CAS 1932275-13-2)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- Ticagrelor Impurity 135 (CAS CATO-C4X-1093135)
- Ticagrelor Impurity 173 (CAS 1212376-05-0)
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 134 (CAS 2165881-71-8)
Recommended Standards
- 21403-26-9 3-chloro-N-(thiophen-2-ylmethyl)propanamide DTXSID10399674 (CAS 21403-26-9)
- 2-Chloro-n-(2-methylcyclohexyl)propanamide (CAS 1005099-41-1)
- 5-Chloro-3-(piperidin-1-yl)-1,2,4-thiadiazole (CAS 41248-07-1)
- 4-Chloro-1-ethyl-1H-indazol-3-amine (CAS 1015846-49-7)
- Rosuvastatin Impurity 145 (CAS CATO-C4X-1169145)
- Dienogest Impurity 17 (CAS 83196-58-1)
- Neratinib Impurity 11 (CAS 1144516-16-4)
- 5-Chloro-4-{[(2,6-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-[(phenylsulfanyl)methyl]-1H-pyrazole (CAS 318248-72-5)
- 2-Bromo-N-((5-(furan-2-yl(hydroxy)methyl)thiophen-2-yl)methyl)benzamide (CAS 1798459-08-1)
- 4-Aminoindolin-5-ol (CAS 121545-80-0)
- 3-(2,5-Dimethylfuran-3-yl)-1h-pyrazol-5-amine (CAS 1028843-17-5)
- Ethyl 2-(4'-(3-methyl-4-(phenylsulfonamido)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetate (CAS 1423683-55-9)
- 5-(methylamino)-2-(naphthalen-1-yl)-1,3-oxazole-4-carbonitrile (CAS 847163-28-4)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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