Efavirenz USP Related Compound C CAS 391860-73-4
| CAS No. | 391860-73-4 |
| Molecular Formula | C13H9ClF3N |
| Molecular Weight | 271.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Efavirenz USP Related Compound C (CAS 391860-73-4, C13H9ClF3N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H9ClF3N, Efavirenz USP Related Compound C contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 271.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H9ClF3N |
| Molecular Weight | 271.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Efavirenz Standards
- Efavirenz Aminoalcohol (CAS 154598-58-0)
- Efavirenz Related Compound A (CAS 209414-27-7)
- Efavirenz Impurity 13 (CAS 927812-33-7)
- Efavirenz USP Related Compound A (CAS 209414-27-7；154598-58-0)
- Efavirenz (CAS 154598-52-4)
- Efavirenz Impurity 10 (CAS 2125704-30-3)
- Efavirenz Impurity 2 (CAS 154801-74-8)
- Efavirenz Impurity 24 (CAS CATO-C4X-162724)
Recommended Standards
- 2-Chloro-6-methyl-4-(4-(trifluoromethyl)phenyl)pyridine (CAS 697739-23-4)
- 5-(3-Chloro-5-fluorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1059171-26-4)
- 2-Benzyl-3-chloro-5-(trifluoromethyl)pyridine (CAS 338419-96-8)
- 5-(Chlorosulfonyl)isoquinoline-1-carboxylic acid (CAS 1258640-93-5)
- Pemafibrate Impurity 59 (CAS CATO-C4X-290359)
- Vildagliptin Impurity 20 (CAS 1983839-19-1)
- Ticagrelor Impurity 183 (CAS CATO-C4X-1093183)
- (5-Isobutoxy-1-methyl-1H-pyrazol-3-yl)methanol (CAS 1707395-79-6)
- Ethyl 2-(6-nitro-1H-indol-1-yl)acetate (CAS 915037-28-4)
- 3-(Trifluoromethyl)pentan-3-amine hydrochloride (CAS 498581-24-1)
- 4-aminopyridazine-3-carboxamide (CAS 20865-28-5)
- 1-Bromo-4-(2-fluoroethoxy)-2-methylbenzene (CAS 1416439-01-4)
- 1-(7-(3-Fluorophenyl)-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one (CAS 691368-95-3)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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