Ezetimibe Impurity 32 CAS 1700622-08-7
| CAS No. | 1700622-08-7 |
| Molecular Formula | C24H21ClFNO3 |
| Molecular Weight | 425.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ezetimibe Impurity 32 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Ezetimibe Impurity 32 (CAS 1700622-08-7, C24H21ClFNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ezetimibe Impurity 32 (C24H21ClFNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H21ClFNO3 |
| Molecular Weight | 425.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 142 (CAS CATO-C4X-1098142)
- EzetimiBe Impurity 19 (CAS 1391053-63-6)
- Ezetimibe Impurity 88 (CAS 1618657-29-6)
- Ezetimibe Impurity 70 (CAS 937636-63-0)
- Ezetimibe Impurity 44 (CAS 204589-82-2)
- Ezetimibe Impurity 18 (CAS 204589-80-0)
- Ezetimibe-13C6 (CAS 438624-68-1)
- Ezetimibe Impurity 117 (CAS 1013025-04-1)
Recommended Standards
- Ls2265 (CAS 72678-30-9)
- 1-(3-Chloro-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide (CAS 1001917-35-6)
- 4-Formyl-2-methoxyphenyl 2-chloro-5-(diethylsulfamoyl)benzoate (CAS 380427-16-7)
- N-(3-Chloro-4-methoxyphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105235-07-1)
- Doxorubicin Impurity 29 (CAS CATO-C4X-203329)
- Amlodipine Besilate EP Impurity B (CAS CATO-C4X-109562)
- Bacampicillin Hydrochloride EP Impurity H (CAS CATO-C4X-173249)
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- Ethyl 2-chloro-4-methyl-3-oxopentanoate (CAS 35391-60-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com