Verapamil Impurity 33 CAS 27487-66-7
| CAS No. | 27487-66-7 |
| Molecular Formula | C16H24N2O2 |
| Molecular Weight | 276.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Verapamil Impurity 33 (CAS 27487-66-7, C16H24N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H24N2O2, Verapamil Impurity 33 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 276.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Verapamil Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H24N2O2 |
| Molecular Weight | 276.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- Verapamil Impurity 20 (CAS 27339-25-9)
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil EP Impurity D (CAS 36770-74-8)
- Verapamil Impurity 17 (CAS CATO-C4X-177817)
- Verapamil EP Impurity F (CAS 34245-14-2)
- Verapamil Impurity 19 (CAS CATO-C4X-177819)
- Verapamil Impurity 51 (CAS CATO-C4X-177851)
- Verapamil Impurity 52 (CAS CATO-C4X-177852)
Recommended Standards
- N-Hydroxy Ropinirole (CAS 954117-22-7)
- N-(4-(methoxymethyl)piperidin-4-yl)-N-phenylpropionamide (CAS 61086-18-8)
- Oxymetazoline Impurity 17 (CAS 756534-85-7)
- Brivaracetam Impurity 151 (CAS CATO-C4X-2007151)
- Pimobendan EP Impurity B (CAS CATO-C4X-246111)
- Siponimod Impurity 30 (CAS CATO-C4X-247230)
- Lenvatinib impurity 166 (CAS CATO-C4X-1140166)
- 1-(1-propylpiperidin-4-yl)piperazine (CAS 1082511-85-0)
- 5-Nitro-1,10-phenanthrolineferroussulfate (CAS 23700-19-8)
- 2-Amino-6-(piperazin-1-yl)pyrimidin-4(3H)-one (CAS 1158775-43-9)
- (S)-2-(1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxamido)-2-methylpropanoic acid (CAS 79118-34-6)
- 6-Fluoro-3-iodo-1-methyl-1H-indazole (CAS 1257535-15-1)
- Diethyl 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarboxylate (CAS 4004-20-0)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com