Verapamil EP Impurity F CAS 34245-14-2
| CAS No. | 34245-14-2 |
| Molecular Formula | C17H26N2O2 |
| Molecular Weight | 290.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Verapamil EP Impurity F (CAS 34245-14-2) is a certified pharmaceutical impurity reference standard with the molecular formula C17H26N2O2 and a molecular weight of 290.41 g/mol.
Structurally, Verapamil EP Impurity F (C17H26N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 290.41 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H26N2O2 |
| Molecular Weight | 290.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- Verapamil Impurity 33 (CAS 27487-66-7)
- Verapamil Impurity 20 (CAS 27339-25-9)
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil EP Impurity D (CAS 36770-74-8)
- Verapamil Impurity 17 (CAS CATO-C4X-177817)
- Verapamil Impurity 18 (CAS 66618-12-0)
- Verapamil Impurity 19 (CAS CATO-C4X-177819)
- Verapamil Impurity 51 (CAS CATO-C4X-177851)
Recommended Standards
- CAS 204259-56-3 (CAS 204259-56-3)
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- Benzo[f][1,7]naphthyridin-5(6H)-one (CAS 52817-50-2)
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- 2-Cyano-3-(difluoromethyl)-5-methylisonicotinic acid (CAS 1805431-01-9)
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