Fluocinolone Acetonide EP Impurity A CAS 106931-78-6
| CAS No. | 106931-78-6 |
| Molecular Formula | C24H28F2O7 |
| Molecular Weight | 466.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Fluocinolone Acetonide EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Fluocinolone Acetonide EP Impurity A (CAS 106931-78-6, C24H28F2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H28F2O7, Fluocinolone Acetonide EP Impurity A contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 466.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H28F2O7 |
| Molecular Weight | 466.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide Impurity 44 (CAS 54605-01-5)
- Fluocinolone Acetonide EP Impurity L (CAS 1893-65-8)
- Fluocinolone Acetonide Impurity 45 (CAS 39987-51-4)
- Fluocinolone Acetonide Impurity N3 (CAS 72498-89-6)
- Fluocinolone Acetonide Impurity 33 (CAS CATO-C4X-238133)
- Fluocinolone Acetonide Impurity N1 (CAS 6598-95-4)
- Fluocinolone Acetonide impurity 19 (CAS CATO-C4X-238119)
- Fluocinolone Acetonide impurity 20 (CAS CATO-C4X-238120)
Recommended Standards
- S-(p-Azidophenacyl)glutathione (CAS 73322-71-1)
- Esaxerenone Impurity 1 (CAS 1072195-83-5)
- Esaxerenone Impurity N4 (CAS 1632006-28-0)
- Esaxerenone Impurity 10 (CAS CATO-C4X-344810)
- Doxofylline Impurity 18 (CAS 42772-85-0)
- Erlotinib Impurity 146 (CAS CATO-C4X-1069146)
- Milrinone Impurity 34 (CAS 1089899-00-2)
- 7429-44-9 Cyclohexanone, 2-methoxy- 2-Methoxycyclohexanone EINECS 231-071-8 (CAS 7429-44-9)
- ((2R,4S,5R)-5-Vinylquinuclidin-2-yl)methanamine (CAS 290817-91-3)
- tert-Butyl 3-methyl-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate (CAS 1782614-12-3)
- Imidazo[1,2-a]pyridine-3-methanamine, 2-methyl-, hydrochloride (CAS 1187932-08-6)
- 2-(2-Hydroxy-4-methoxyphenyl)-4,6-diphenyl-1,3,5-triazine (CAS 106556-36-9)
- Desloratadine Impurity 61 (CAS CATO-C4X-143061)
- Custom peptides (CAS CATO-CPTD788509)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com