Fluocinolone Acetonide Impurity 45 CAS 39987-51-4
| CAS No. | 39987-51-4 |
| Molecular Formula | C25H31FO7 |
| Molecular Weight | 462.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fluocinolone Acetonide Impurity 45 (C25H31FO7) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Fluocinolone Acetonide Impurity 45 (CAS 39987-51-4), a pharmacopoeial impurity reference standard (molecular formula C25H31FO7, MW 462.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H31FO7 |
| Molecular Weight | 462.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide Impurity 44 (CAS 54605-01-5)
- Fluocinolone Acetonide Impurity N3 (CAS 72498-89-6)
- Fluocinolone Acetonide Impurity 33 (CAS CATO-C4X-238133)
- Fluocinolone Acetonide EP Impurity A (CAS 106931-78-6)
- Fluocinolone Acetonide EP Impurity L (CAS 1893-65-8)
- Fluocinolone Acetonide-13C3 (CAS 1262192-25-5)
- Fluocinolone Acetonide Impurity 31 (CAS 1178-54-7)
- Fluocinolone Acetonide Impurity 3 (CAS 4306-83-6)
Recommended Standards
- 3-Amino-N-(4-methyl-1,3-benzothiazol-2-yl)-4-(trifluoromethyl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 664999-47-7)
- Z-Arg(Tos)-OH (CAS 13650-38-9)
- Carbamic acid, N-[(1S)-2-[[(1S)-3-fluoro-2-oxo-1-(phenylmethyl)propyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester (CAS 105608-85-3)
- N-(4-(4-Methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidin-2-amine (CAS 1353553-08-8)
- Abiraterone Impurity 38 (CAS CATO-C4X-107038)
- Orforglipron impurity 128 (CAS CATO-C4X-3234128)
- Moxifloxacin EP Impurity H (CAS 721970-35-0)
- Levothyroxine Impurity 29（Mixture of Diastereomers） (CAS CATO-C4X-167829)
- Tert-butyl tert-butylalaninate (CAS 92147-82-5)
- 5-(Benzyloxy)-6-(hydroxymethyl)picolinaldehyde (CAS 38029-04-8)
- 3-Bromo-5-chlorothiophene-2-sulfonyl chloride (CAS 175205-72-8)
- (R)-1-Boc-3-carboxymethoxy-pyrrolidine (CAS 170097-85-5)
- (3-(4-Aminophenyl)-5-methylisoxazol-4-yl)(4-(2-chloro-4-nitrophenyl)piperazin-1-yl)methanone (CAS 1264870-22-5)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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