Beclometasone Impurity 52 CAS CATO-C4X-147452
| CAS No. | CATO-C4X-147452 |
| Molecular Formula | C28H37ClO7 |
| Molecular Weight | 521.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Beclometasone Impurity 52 (CAS CATO-C4X-147452), a pharmacopoeial impurity reference standard (molecular formula C28H37ClO7, MW 521.04 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Beclometasone Impurity 52 (C28H37ClO7) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Beclometasone Impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H37ClO7 |
| Molecular Weight | 521.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Beclometasone Standards
- Beclometasone Dipropionate EP Impurity M (CAS 3100114-15-3)
- Beclometasone Dipropionate Monohydrate EP Impurity L (CAS 114371-33-4)
- Beclometasone dipropionate EP Impurity B (CAS 5534-08-7)
- Beclometasone Dipropionate Monohydrate EP Impurity C (CAS CATO-C4X-14743)
- Beclometasone Dipropionate Monohydrate EP Impurity O (CAS 14527-61-8)
- Beclometasone Impurity 51 (CAS CATO-C4X-147451)
- Beclometasone Dipropionate Monohydrate EP Impurity E (CAS 887130-68-9)
- Beclometasone Impurity 43 (CAS CATO-C4X-147443)
Recommended Standards
- Alclometasone 17,21-Dipropionate (CAS 66734-13-2)
- Betamethasone Dipropionate EP Impurity E (CAS 5534-09-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com