Loratadine Impurity 41 CAS CATO-C4X-142641
| CAS No. | CATO-C4X-142641 |
| Molecular Formula | C25H30ClN3O2 |
| Molecular Weight | 439.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Loratadine Impurity 41 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Loratadine Impurity 41 (CAS CATO-C4X-142641, C25H30ClN3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C25H30ClN3O2, Loratadine Impurity 41 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 439.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Loratadine Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H30ClN3O2 |
| Molecular Weight | 439.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loratadine Standards
- Loratadine Impurity 43 (CAS CATO-C4X-142643)
- Loratadine Impurity 53 (CAS CATO-C4X-142653)
- Loratadine Impurity 100 (CAS CATO-C4X-1426100)
- Loratadine Impurity 55 (CAS CATO-C4X-142655)
- Loratadine Impurity 81 (CAS CATO-C4X-142681)
- Loratadine Impurity 25 (CAS CATO-C4X-142625)
- Loratadine impurity 21 (CAS CATO-C4X-142621)
- Loratadine impurity 22 (CAS CATO-C4X-142622)
Recommended Standards
- Montelukast Impurity 37 (CAS CATO-C4X-103137)
- 4-Iodo-2-heptafluoropropoxy-1,1,1,2-tetrafluorobutane (CAS 243128-38-3)
- Montelukast Impurity 32 (CAS 1187586-63-5)
- Heptafluoroisopropyl 4-iodo-1,1,2,2-tetrafluorobut-1-yl ether (CAS 25080-20-0)
- Vericiguat Impurity 33 (CAS CATO-C4X-289633)
- Alectinib impurity 24 (CAS 1256585-32-6)
- Mirogabalin Impurity 134 (CAS CATO-C4X-2924134)
- tert-butyl 2-(piperidin-4-yl)benzoate (CAS 1803600-82-9)
- 3-azidothiophene-2-carbaldehyde (CAS 56473-97-3)
- 4-Ethyl-2-mercapto-6,7-dihydro-5h-cyclopenta[b]pyridine-3-carbonitrile (CAS 213203-86-2)
- 3'-O-Methylbatatasin III (CAS 101330-69-2)
- 2-(4-(Difluoromethyl)-5-fluoro-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1806021-47-5)
- (2R,6S)-2,6-Diaminoheptanedioic acid (CAS 1356383-43-1)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com