Nintedanib Impurity 99 CAS CATO-C4X-181499
| CAS No. | CATO-C4X-181499 |
| Molecular Formula | C16H16N4O5 |
| Molecular Weight | 344.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 344.32 g/mol gives Nintedanib Impurity 99 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Nintedanib Impurity 99 (CAS CATO-C4X-181499, C16H16N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Nintedanib Impurity 99 (C16H16N4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 344.32 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 99 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16N4O5 |
| Molecular Weight | 344.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Nintedanib Standards
- Nintedanib Impurity 134 (CAS CATO-C4X-1814134)
- Nintedanib Impurity 119 (CAS CATO-C4X-1814119)
- Nintedanib Impurity 128 (CAS CATO-C4X-1814128)
- Nintedanib Impurity 13 (CAS 1253769-13-9)
- Nintedanib Impurity 49 (CAS 1168152-07-5)
- Nintedanib Impurity 148 (CAS CATO-C4X-1814148)
- Nintedanib Impurity 162 (CAS CATO-C4X-1814162)
- Nintedanib Impurity 164 (CAS CATO-C4X-1814164)
Recommended Standards
- Nifedipine EP Impurity A (CAS 67035-22-7)
- Nitrendipine impurity 21 (CAS 1195583-65-3)
- 214843-13-7 Coccineone E (CAS 214843-13-7)
- Nitrendipine Impurity 3 (CAS 76258-20-3)
- Carvedilol impurity 22 (CAS 142227-49-4)
- Estradiol Impurity 42 (CAS CATO-C4X-163642)
- Posaconazole Impurity 86 (CAS CATO-C4X-1208186)
- 5-Methyl-2-(p-tolylamino)thiazole-4-carboxylic acid (CAS 1550325-40-0)
- Betamethasone impurity 48 (CAS CATO-C4X-143748)
- 4-(3-Chlorophenyl)oxane-4-carboxylic acid (CAS 473706-23-9)
- [[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-fluoro-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate (CAS 202186-97-8)
- 5-Chloro-2-(3-chloro-4-fluorophenoxy)aniline (CAS 946715-14-6)
- 2,3-Butanediol (CAS 513-85-9)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com