Dabrafenib Impurity N7 CAS 1195768-23-0
| CAS No. | 1195768-23-0 |
| Molecular Formula | C23H18ClF3N4O2S2 |
| Molecular Weight | 538.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dabrafenib Impurity N7 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dabrafenib Impurity N7 (CAS 1195768-23-0, C23H18ClF3N4O2S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H18ClF3N4O2S2, Dabrafenib Impurity N7 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 538.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dabrafenib Impurity N7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H18ClF3N4O2S2 |
| Molecular Weight | 538.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity N2 (CAS 1195767-77-1)
- Dabrafenib Impurity 37 (CAS CATO-C4X-303337)
- Dabrafenib Impurity 38 (CAS 3052138-43-6)
- Dabrafenib Impurity 9 (CAS CATO-C4X-30339)
- Dabrafenib Impurity 36 (CAS CATO-C4X-303336)
- Dabrafenib Impurity 19 (CAS 1907654-22-1)
- Dabrafenib Impurity 12 (CAS CATO-C4X-303312)
- Dabrafenib Impurity 15 (CAS CATO-C4X-303315)
Recommended Standards
- Pyr-Pro-Arg-pNA (CAS 72194-57-1)
- Bis(2,4,6-trichlorophenyl) 2-phenylmalonate (CAS 15781-73-4)
- Allisartan Isoproxil Impurity 27 (CAS 947331-07-9)
- 3,3',5,5'-Tetrakis((trimethylsilyl)ethynyl)-1,1'-biphenyl (CAS 1613462-65-9)
- Tamsulosin EP Impurity G HCl (CAS 106463-19-8)
- Zidovudine Impurity 04 (CAS 73971-82-1)
- Apixaban Impurity 113 (CAS 617-84-5)
- D-(-)-2,3-diphosphoglyceric Acid (CAS 14438-19-8)
- (1s)-1-(6-Bromo(3-pyridyl))ethylamine (CAS 1213594-37-6)
- 5-Fluoro-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1774896-93-3)
- 4-Oxo-1,4-dihydrothieno[2,3-d]pyrimidine-5-carboxylic acid (CAS 1104926-91-1)
- Methyl 2-amino-4-(4-chloro-3,5-dimethyl-1h-pyrazol-1-yl)butanoate (CAS 1343966-80-2)
- Trichlorobis(dimethylsulfoxide)imidazoleruthenium(III) (CAS 141624-71-7)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com