Dabrafenib Impurity 37 CAS CATO-C4X-303337
| CAS No. | CATO-C4X-303337 |
| Molecular Formula | C23H20F3N5O3S2 |
| Molecular Weight | 535.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Dabrafenib Impurity 37 (CAS CATO-C4X-303337, C23H20F3N5O3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Dabrafenib Impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 535.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dabrafenib Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H20F3N5O3S2 |
| Molecular Weight | 535.56 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity N2 (CAS 1195767-77-1)
- Dabrafenib Impurity 38 (CAS 3052138-43-6)
- Dabrafenib Impurity 9 (CAS CATO-C4X-30339)
- Dabrafenib Impurity 19 (CAS 1907654-22-1)
- Dabrafenib Impurity N7 (CAS 1195768-23-0)
- Dabrafenib Impurity 12 (CAS CATO-C4X-303312)
- Dabrafenib-D9 (CAS 1423119-98-5)
- Dabrafenib Impurity 36 (CAS CATO-C4X-303336)
Recommended Standards
- 4-Methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 882663-88-9)
- O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 (CAS 1356354-05-6)
- (11bS)-N-Allyl-N-(9H-fluoren-9-yl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 2375836-80-7)
- Sotorasib impurity 1 (CAS CATO-C4X-31031)
- Avanafil Impurity 14 (CAS CATO-C4X-111814)
- Halometasone Impurity 9 (CAS CATO-C4X-14469)
- Itraconazole Impurity 82 (CAS CATO-C4X-149782)
- pregabalin Impurity 36 (CAS 181289-16-7)
- Fluoxetine Impurity 4 (CAS 402-45-9)
- 5-Cyclopropoxy-6-iodo-N,N-dimethylpicolinamide (CAS 1243311-87-6)
- 4-Cyclopropyl-5-((5-methyl-1h-pyrazol-1-yl)methyl)-4h-1,2,4-triazole-3-thiol (CAS 1001500-09-9)
- 2,2,2-Trifluoro-1-(4-fluoro-2-(isopentyloxy)phenyl)ethanone (CAS 1443310-49-3)
- 2-Furoic acid, 5-[(Ethylthio)methyl]- (CAS 106166-79-4)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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