Avatrombopag Impurity 52 CAS 1224935-95-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1224935-95-8
Molecular FormulaC15H28N2O2
Molecular Weight268.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Avatrombopag Impurity 52 CAS 1224935-95-8 chemical structure

Description

The occurrence of Avatrombopag Impurity 52 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Avatrombopag Impurity 52 (CAS 1224935-95-8) is a certified pharmaceutical impurity reference standard with the molecular formula C15H28N2O2 and a molecular weight of 268.40 g/mol.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, Avatrombopag Impurity 52 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Avatrombopag Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H28N2O2
Molecular Weight268.40 g/mol
AppearanceWhite to pale yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1990
Nitrogen Atoms2

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