Avatrombopag Impurity 96 CAS CATO-C4X-223496
| CAS No. | CATO-C4X-223496 |
| Molecular Formula | C11H8Cl2O4 |
| Molecular Weight | 275.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Avatrombopag Impurity 96 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Avatrombopag Impurity 96 (CAS CATO-C4X-223496) is a certified pharmaceutical impurity reference standard with the molecular formula C11H8Cl2O4 and a molecular weight of 275.08 g/mol.
Based on its molecular formula C11H8Cl2O4, Avatrombopag Impurity 96 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 275.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avatrombopag Impurity 96 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8Cl2O4 |
| Molecular Weight | 275.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Avatrombopag Standards
- Avatrombopag Impurity 52 (CAS 1224935-95-8)
- Avatrombopag Impurity 67 (CAS 901314-75-8)
- Avatrombopag Impurity 18 (CAS 958457-83-5)
- Avatrombopag Impurity 114 (CAS CATO-C4X-2234114)
- Avatrombopag Impurity 71 (CAS 252263-38-0)
- Avatrombopag Impurity 86 (CAS 81216-89-9)
- Avatrombopag Impurity 144 (CAS CATO-C4X-2234144)
- Avatrombopag impurity 134 (CAS CATO-C4X-2234134)
Recommended Standards
- Methyl 4-(3,4-dichlorophenyl)-2,4-dioxobutanoate (CAS 374679-63-7)
- N-(3-Iodobenzyl)acetamide (CAS 104291-06-7)
- Methyl 4-(2,5-dichlorophenyl)-2,4-dioxobutanoate (CAS 848052-90-4)
- 2-(Bromodifluoromethyl)-1-phenyl-4,5-dihydro-1H-imidazole (CAS 1069085-29-5)
- Ethambutol EP Impurity C DiHCl (CAS 134566-79-3)
- Loxoprofen impurity 126 (CAS CATO-C4X-1488126)
- Ketoconazole impurity 30 (CAS CATO-C4X-147230)
- 5-fluoro-1H-pyrrolo[2,3-b]pyridin-6-ol (CAS 1190316-03-0)
- 2-(2-Bromo-6-fluoro-4-methylphenyl)-1,3-dioxolane (CAS 2221812-28-6)
- (r)-5-(1-Amino-2-hydroxyethyl)-2-methoxyphenol (CAS 1212853-97-8)
- 3-[3-(diethylamino)propyl]-2-mercaptoquinazolin-4(3H)-one (CAS 422526-36-1)
- 1,4-Diamino-7-chloro-2-(4-chlorophenoxy)anthracene-9,10-dione (CAS 88605-29-2)
- 5-Cyclopropyl-3-(4-methylphenyl)-1,2,4-oxadiazole (CAS 884635-91-0)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
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