Sofosbuvir Impurity 51 CAS 1233335-78-8
| CAS No. | 1233335-78-8 |
| Molecular Formula | C13H19FN3O9P |
| Molecular Weight | 411.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sofosbuvir Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Sofosbuvir Impurity 51 (CAS 1233335-78-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H19FN3O9P and a molecular weight of 411.28 g/mol.
Based on its molecular formula C13H19FN3O9P, Sofosbuvir Impurity 51 contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 411.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H19FN3O9P |
| Molecular Weight | 411.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 89 (CAS CATO-C4X-105289)
- Sofosbuvir Impurity 95 (CAS CATO-C4X-105295)
- Sofosbuvir Impurity 97 (CAS 1911578-88-5)
- Sofosbuvir Impurity 85 (CAS 1621160-31-3)
- Sofosbuvir Impurity 68 (CAS 1496551-65-5)
- Sofosbuvir Impurity 96 (CAS 1392015-05-2)
- Sofosbuvir Impurity 84 (CAS 914912-69-9)
- Sofosbuvir Impurity 1 (CAS 1033394-94-3)
Recommended Standards
- Nor-PE 2I (CAS 311351-26-5)
- tert-Butyl (S)-2-((2-(4-bromophenyl)-2-oxoethyl)carbamoyl)pyrrolidine-1-carboxylate (CAS 1007881-98-2)
- N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxybenzamide (CAS 61439-05-2)
- 2-(4-Bromophenyl)-1-(6-methoxypyridin-3-yl)-6-methyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1022648-64-1)
- Bilastine Impurity 67 (CAS 1181267-38-8)
- Oclacitinib impurity 8 (CAS CATO-C4X-30188)
- Biotin impurity 39 (CAS CATO-C4X-156339)
- 4-Bromo-3-methoxy-1,2-thiazole (CAS 31815-40-4)
- 1-Methyl-4-phenyl-4-piperidinol (CAS 4972-68-3)
- 3,5-Bis(3-(difluoromethoxy)phenyl)-1h-pyrazole (CAS 1159988-69-8)
- 2-(aminomethyl)bicyclo[2.2.1]heptan-2-ol (CAS 45731-39-3)
- 2-Azabicyclo[2.2.2]octane-3-carboxylic acid (CAS 90103-87-0)
- Ac-Phe-pNA (CAS 17682-83-6)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com