Diclofenac Sodium Impurity 34 CAS 123790-84-1
| CAS No. | 123790-84-1 |
| Molecular Formula | C12H9BrClN |
| Molecular Weight | 282.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Diclofenac Sodium Impurity 34 (CAS 123790-84-1), a pharmacopoeial impurity reference standard (molecular formula C12H9BrClN, MW 282.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Diclofenac Sodium Impurity 34 (C12H9BrClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 282.56 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Diclofenac Sodium Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9BrClN |
| Molecular Weight | 282.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Sodium Impurity 35 (CAS 13625-57-5)
- Diclofenac impurity N2 (CAS 84803-53-2)
- Diclofenac sodium Impurity 58 (CAS 848060-64-0)
- Diclofenac acid Impurity 59 (CAS 304884-75-1)
- Diclofenac impurity 8 (CAS CATO-C4X-16148)
- Diclofenac EP Impurity A (CAS 15362-40-0)
- Diclofenac Impurity 45 (CAS 24542-74-3)
- Diclofenac Impurity 22 (CAS CATO-C4X-105122)
Recommended Standards
- 7-Bromo-9-chloro-2,3-dihydro-1H-cyclopenta[b]quinoline (CAS 40528-06-1)
- 2-Chloro-5-methoxymethylphenylboronic acid pinacol ester (CAS 1079402-22-4)
- 4-(4-Bromo-3-methylphenyl)-2-chloropyridine (CAS 1539429-62-3)
- 2-Chloro-N,N-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine (CAS 1201845-13-7)
- Tafluprost Impurity 19 (CAS CATO-C4X-216319)
- Valsartan Impurity 74 (CAS CATO-C4X-105774)
- Rosuvastatin Impurity 162 (CAS 488798-40-9)
- 3-Chloro-N-(2-fluoro-4-methylphenyl)benzamide (CAS 1037953-69-7)
- 3-Methyl-1-phenyl-1h-pyrazolo[3,4-b]pyridine-6-carboxylic acid (CAS 1274506-24-9)
- 2-(1-Methyl-2-oxoindolin-3-ylidene)malononitrile (CAS 39081-26-0)
- (R)-2-allylpyrrolidine-2-carboxylic acid (CAS 121772-98-3)
- 5-Amino-1-methyl-1H-pyrazole-4-carbothioamide (CAS 956534-58-0)
- Methyl 2-bromo-4,5-dimethoxybenzoate (CAS 17667-32-2)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com