Valsartan Impurity 74 CAS CATO-C4X-105774
| CAS No. | CATO-C4X-105774 |
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Valsartan Impurity 74 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Valsartan Impurity 74 (CAS CATO-C4X-105774) is a certified pharmaceutical impurity reference standard with the molecular formula C25H31N5O3 and a molecular weight of 449.55 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Valsartan Impurity 74 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 449.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
- Valsartan Impurity 112 (CAS CATO-C4X-1057112)
- Valsartan Impurity 120 (CAS 137863-48-0)
- Valsartan Impurity 125 (CAS 1894176-40-9)
- Valsartan USP Related Compound E (CAS 137863-17-3)
- Valsartan Impurity 73 (CAS CATO-C4X-105773)
- Valsartan Impurity 75 (CAS CATO-C4X-105775)
- Valsartan Impurity 76 (CAS CATO-C4X-105776)
Recommended Standards
- Valsartan Impurity 77 (CAS CATO-C4X-105777)
- Valsartan Impurity 78 (CAS CATO-C4X-105778)
- Valsartan Impurity 8 (CAS 137862-78-3)
- Valsartan Impurity 83 (CAS CATO-C4X-105783)
- Cyclosporin Impurity 19 (CAS 2715287-08-2)
- Dapoxetine Impurity 79 (CAS CATO-C4X-143979)
- Spironolactone Impurity 14 (CAS 53866-20-9)
- N-Ethyl-2-(2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)thiazol-4-yl)acetamide (CAS 946200-04-0)
- 3-Cyclopropoxy-N2-methylpyridine-2,6-dicarboxamide (CAS 1243446-61-8)
- 4-(4-Fluoro-2-methylphenoxy)piperidine (CAS 367501-10-8)
- (R)-2-Amino-3-benzyloxy-1-propanol (HCl salt) (CAS 58577-95-0)
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- 110207-62-0 Acetyl-Cholecystokinin Octapeptide (2-8) (sulfated) MFCD00133565 (CAS 110207-62-0)
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