Dasatinib Impurity N57 CAS 1245157-42-9
| CAS No. | 1245157-42-9 |
| Molecular Formula | C15H20N6O3S |
| Molecular Weight | 364.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Dasatinib Impurity N57 (CAS 1245157-42-9, C15H20N6O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dasatinib Impurity N57 (C15H20N6O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 364.42 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dasatinib Impurity N57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H20N6O3S |
| Molecular Weight | 364.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 74 (CAS CATO-C4X-160774)
- Dasatinib impurity 67 (CAS 302964-06-3)
- Dasatinib Impurity 46 (CAS CATO-C4X-160746)
- Dasatinib impurity 60 (CAS CATO-C4X-160760)
- Dasatinib Impurity 55 (CAS CATO-C4X-160755)
- Dasatinib Impurity 29 (CAS CATO-C4X-160729)
- Dasatinib Dichloro Impurity (CAS 302964-08-5)
- Dasatinib Impurity 73 (CAS CATO-C4X-160773)
Recommended Standards
- Bumetanide (CAS 28395-03-1)
- 110382-37-1 Propanoic acid,2-methyl-,2,3,3a,4,5,6,9,11b-octahydro-9-methoxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-ylester, [3aR-(3aR*,4R*,6R*,9R*,10Z,11aR*)]- (9CI) (CAS 110382-37-1)
- Bumetanide Impurity 97 (CAS 28328-60-1)
- 5-Hydroxy Omeprazole-(Pyridyl)-d (CAS 1189882-58-3)
- Mesalazine Impurity 46 (CAS 34662-36-7)
- Formoterol impound 144 (CAS 343618-74-6)
- Axitinib Impurity 82 (CAS CATO-C4X-107182)
- 3-amino-4-(difluoromethoxy)benzoic acid (CAS 1096879-61-6)
- 2-(4-Bromo-1-chlorobutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 123948-26-5)
- 1-(Chloromethoxy)-2-fluorobenzene (CAS 1394288-17-5)
- (R)-4-Boc-piperazine-2-carboxylic Acid (CAS 192330-11-3)
- 2-Methyl-2-(1-methyl-1h-pyrazol-4-yl)propanoic acid (CAS 1249313-28-7)
- N-(4-Acetylphenyl)-3-(5-ethylfuran-2-yl)acrylamide (CAS 890605-54-6)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com