2'-Chloro-2-fluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid CAS 1261904-84-0
| CAS No. | 1261904-84-0 |
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2'-Chloro-2-fluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid.
2'-Chloro-2-fluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261904-84-0) is a high-purity analytical reference standard with the molecular formula C14H10ClFO3 and a molecular weight of 280.68 g/mol.
Based on its molecular formula C14H10ClFO3, 2'-Chloro-2-fluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 280.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2'-Chloro-2-fluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFO3 |
| Molecular Weight | 280.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-((3-fluorobenzyl)oxy)benzoic acid (CAS 1002312-89-1)
- 2-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1019348-55-0)
- 1-(3-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 1038738-53-2)
- 5-chloro-6-[(5-fluoro-2-methylphenyl)amino]pyridine-3-carboxylic acid (CAS 1040006-05-0)
- 4-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041536-98-4)
- 3-((2-Chloro-4-fluorobenzyl)oxy)benzoic acid (CAS 1041558-34-2)
- 2-(2-Chloro-4-fluorophenoxy)-2-phenylacetic acid (CAS 1082401-01-1)
- 3-Chloro-5'-fluoro-2'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 1097085-11-4)
Recommended Standards
- 2-Chloro-4-(4-fluoro-3-methoxyphenyl)benzoic acid (CAS 1261892-14-1)
- 3'-Chloro-5'-fluoro-5-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261922-66-0)
- 2-(2-(4-Fluorophenoxy)-5-chlorophenyl)acetic Acid (CAS 1242014-98-7)
- 4-(4-Chloro-2-methoxyphenyl)-3-fluorobenzoic acid (CAS 1261970-23-3)
- 5-((Methylthio)methyl)piperazin-2-one (CAS 907973-10-8)
- Methyl (((9H-fluoren-9-yl)methoxy)carbonyl)tyrosinate (CAS 1270300-64-5)
- 2-Methyl-6-nitrobenzo[d]oxazol-4-ol (CAS 88172-84-3)
- 2-Amino-4-(trifluoromethyl)phenol (CAS 454-81-9)
- 2-(4-Imino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-3(4H)-yl)ethan-1-ol (CAS 342396-95-6)
- Eltrombopag Impurity 107 (CAS CATO-C4X-1198107)
- Buta-1,3-dien-1-yltriphenylphosphonium bromide (CAS 21310-07-6)
- 2-((4-Chlorobenzyl)sulfinyl)-1,1-diphenylethan-1-ol (CAS 252026-50-9)
- 9-O-Methyl-4-hydroxyboeravinone B (CAS 333798-10-0)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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