Trazodone Impurity 4 CAS 1263278-79-0
| CAS No. | 1263278-79-0 |
| Molecular Formula | C19H21Cl2N5O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Trazodone Impurity 4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 442.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Trazodone Impurity 4 (CAS 1263278-79-0, C19H21Cl2N5OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Trazodone Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21Cl2N5O HCl |
| Molecular Weight | 442.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Trazodone Standards
- Trazodone Impurity N13 (CAS 101364-27-6)
- Trazodone D6 (CAS 1181578-48-2)
- Trazodone-d6 Hydrochloride (CAS 1181578-71-1)
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Trazodone EP Impurity D HCl (CAS 1263278-80-3)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone EP Impurity D (CAS 1263358-13-9)
- Trazodone EP Impurity E (CAS 1346599-35-6)
Recommended Standards
- Empagliflozin Impurity 294 (CAS CATO-C4X-1065294)
- Sapropterin Impurity 2 (CAS CATO-C4X-27662)
- Cefepime EP Impurity F (CAS CATO-C4X-11936)
- (3Alpha)-3-chloro-cholest-4-ene (CAS 13901-10-5)
- Diphenyl terephthalate (CAS 1539-04-4)
- 3,6-Bis-(Methoxymethyl)durene (CAS 1424-78-8)
- 5-(2-Amino-6-phenyl-6H-1,3-thiazin-4-yl)-4-methoxybenzofuran-6-ol (CAS 61340-62-3)
- 1-[1-(2-methylphenyl)-2-nitropropyl]-1H-pyrazole (CAS 1803582-77-5)
- 5-(tert-Butyl)-2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)benzaldehyde (CAS 1242157-07-8)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com