Etravirine Impurity 1 CAS 1263409-98-8
| CAS No. | 1263409-98-8 |
| Molecular Formula | C13H9Cl2N3O |
| Molecular Weight | 294.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H9Cl2N3O, Etravirine Impurity 1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 294.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Etravirine Impurity 1 (CAS 1263409-98-8) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9Cl2N3O and a molecular weight of 294.14 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Etravirine Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9Cl2N3O |
| Molecular Weight | 294.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Etravirine Standards
- Etravirine Impurity 5 (CAS 1398507-09-9)
- Etravirine Impurity N1 (CAS 939431-68-2)
- Etravirine Impurity 4 (CAS CATO-C4X-13564)
- Etravirine Impurity N2 (CAS 1070377-34-2)
- Etravirine 6-Desamino 5-Chloro Impurity (CAS 269055-05-2)
- Etravirine Impurity 2 (CAS 1225383-64-1)
- Etravirine Impurity 3 (CAS CATO-C4X-13563)
- Etravirine Iimpurity 9 (CAS 269055-19-8)
Recommended Standards
- (S)-4-Bromo-2-((tert-butoxycarbonyl)amino)pent-4-enoic acid (CAS 151215-34-8)
- N-(3-bromophenyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide (CAS 1015523-74-6)
- n-(4-Bromophenyl)-3-(furan-2-yl)propanamide (CAS 882112-86-9)
- 1-(4-Bromophenyl)-2-methyl-2-(1H-1,2,4-triazol-1-yl)propan-1-one (CAS 1020252-47-4)
- Paclitaxel EP Impurity C (CAS 153415-45-3)
- Letermovir Impurity 42 (CAS CATO-C4X-291542)
- Encorafenib Impurity 12 (CAS CATO-C4X-324912)
- 6-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrate (CAS 1609402-71-2)
- 1,3-Di-tert-butyl 2-sulfanylideneimidazolidine-1,3-dicarboxylate (CAS 173300-83-9)
- Methyl 3-(4-bromo-1H-benzo[d]imidazol-2-yl)propanoate (CAS 1420792-89-7)
- 2,2,2-Trifluoroacetic acid compound with 2-(3-acetyl-1H-pyrrolo[2,3-c]pyridin-1-yl)acetic acid (1:1) (CAS 1386457-06-2)
- 8-Bromoadenine (CAS 6974-78-3)
- 1-(4-Chlorophenyl)-2-methoxyethan-1-amine (CAS 391233-75-3)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com