Etravirine Impurity 4 CAS CATO-C4X-13564
| CAS No. | CATO-C4X-13564 |
| Molecular Formula | C20H16N6O |
| Molecular Weight | 356.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 356.38 g/mol gives Etravirine Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Etravirine Impurity 4 (CAS CATO-C4X-13564, C20H16N6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Etravirine Impurity 4 (C20H16N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Etravirine Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H16N6O |
| Molecular Weight | 356.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Etravirine Standards
- Etravirine Impurity N1 (CAS 939431-68-2)
- Etravirine Impurity N2 (CAS 1070377-34-2)
- Etravirine 6-Desamino 5-Chloro Impurity (CAS 269055-05-2)
- Etravirine Impurity 2 (CAS 1225383-64-1)
- Etravirine Impurity 3 (CAS CATO-C4X-13563)
- Etravirine Impurity 5 (CAS 1398507-09-9)
- Etravirine Iimpurity 9 (CAS 269055-19-8)
- Etravirine Impurity 1 (CAS 1263409-98-8)
Recommended Standards
- Dabigatran Impurity 113 (CAS CATO-C4X-1089113)
- S-Adenosyl-L-Methionine Impurity 28 (CAS CATO-C4X-138128)
- Dabigatran Impurity 107 (CAS CATO-C4X-1089107)
- Ruxolitinib Impurity 119 (CAS CATO-C4X-2058119)
- Tegoprazan Impurity 79 (CAS CATO-C4X-229779)
- Mianserin Impurity 89 (CAS CATO-C4X-136989)
- Diclofenac Impurity N1 (CAS 131023-43-3)
- 4-Methyl-2-(2-oxopropylidene)oxazolidin-5-one (CAS 28897-82-7)
- 4-Chloro-2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrazine (CAS 1255783-50-6)
- (Z)-{[3-nitro-4-(piperidin-1-yl)phenyl]methylidene}amino 4-methylbenzoate (CAS 339019-81-7)
- 4-(2,6-dimethylphenoxy)piperidine (CAS 1017048-01-9)
- 2-(4-Methyl-3-nitrophenyl)acetonitrile (CAS 82613-51-2)
- 5-chloro-2H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1520692-02-7)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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