Etravirine Impurity N1 CAS 939431-68-2
| CAS No. | 939431-68-2 |
| Molecular Formula | C20H16N6O |
| Molecular Weight | 356.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Etravirine Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Etravirine Impurity N1 (CAS 939431-68-2), a pharmacopoeial impurity reference standard (molecular formula C20H16N6O, MW 356.38 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Etravirine Impurity N1 (C20H16N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H16N6O |
| Molecular Weight | 356.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
Related Etravirine Standards
- Etravirine Impurity 4 (CAS CATO-C4X-13564)
- Etravirine Impurity N2 (CAS 1070377-34-2)
- Etravirine 6-Desamino 5-Chloro Impurity (CAS 269055-05-2)
- Etravirine Impurity 2 (CAS 1225383-64-1)
- Etravirine Impurity 3 (CAS CATO-C4X-13563)
- Etravirine Impurity 5 (CAS 1398507-09-9)
- Etravirine Iimpurity 9 (CAS 269055-19-8)
- Etravirine Impurity 1 (CAS 1263409-98-8)
Recommended Standards
- Ethyl 2-imino-1-(2-methoxyethyl)-10-methyl-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 371116-82-4)
- Methyl 1-(3-ethoxypropyl)-2-imino-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 510762-89-7)
- Diphenyl((phenylsulfonyl)methyl)phosphine oxide (CAS 94333-12-7)
- Methyl 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)benzoate (CAS 886444-10-6)
- Finerenone Impurity 203 (CAS CATO-C4X-2880203)
- Ticagrelor Impurity 108 (CAS 2417798-14-0)
- Iohexol impurity 40 (CAS CATO-C4X-166440)
- 6-Bromo-3-hydroxy-2-phenyl-3,4-dihydroquinazolin-4-one (CAS 477864-80-5)
- 2-Bromo-4,6-difluorobenzamide (CAS 1805422-78-9)
- 5-Bromoisoxazolo[5,4-b]pyridine (CAS 1246552-55-5)
- (Z)-Pelubiprofen (CAS CATO-C4X-21272)
- Defluoro Levofloxacin-d3 (CAS 1329836-14-7)
- rel-(βS)-β,3-Dihydroxy-D-tyrosine (CAS 3916-18-5)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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