Trametinib Impurity 12 CAS 1279693-89-8
| CAS No. | 1279693-89-8 |
| Molecular Formula | C24H19FIN5O5 |
| Molecular Weight | 603.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, Trametinib Impurity 12 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 603.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Trametinib Impurity 12 (CAS 1279693-89-8), a certified reference material (molecular formula C24H19FIN5O5, MW 603.34 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Trametinib Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H19FIN5O5 |
| Molecular Weight | 603.34 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 5 |
Related Trametinib Standards
- Trametinib impurity 04 (CAS 871700-25-3)
- Trametinib Impurity N11 (CAS 871701-23-4)
- Trametinib (CAS 871700-17-3)
- Trametinib impurity 4 (CAS CATO-C4X-27824)
- Trametinib Impurity N5 (CAS 1620017-29-9)
- Trametinib-13C-d3 (CAS 2712126-59-3)
- Trametinib impurity 26 (CAS CATO-C4X-27826)
- Trametinib Impurity N2 (CAS 871701-39-2)
Recommended Standards
- (2S,3S,4R,5R)-2-azido-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(iodomethyl)tetrahydrofuran-3,4-diyl dibenzoate (CAS 139419-02-6)
- 2-[Butyl[(Pentadecafluoroheptyl)Sulphonyl]Amino]Ethyl Acrylate (CAS 68298-60-2)
- 2',7'-Dibromo-5H-spiro[dibenzo[c,h]acridine-7,9'-fluoren]-5-one (CAS 1345890-47-2)
- Empagliflozin Impurity 87 (CAS CATO-C4X-1065287)
- Benzophenone 9 (CAS 76656-36-5)
- 2-Amino-6-(cyclopentylamino)pyrimidin-4(3H)-one (CAS 7400-24-0)
- N-(4-{[(4Z)-5-oxo-2-sulfanylideneimidazolidin-4-ylidene]methyl}phenyl)acetamide (CAS 103984-21-0)
- N-(furan-2-ylmethyl)thietan-3-amine (CAS 1499735-98-6)
- 7-Oxo-7H-[1,3]thiazolo[3,2-a]pyrimidine-5-carboxylic acid hydrate (CAS 1609395-62-1)
- 6-(Piperidin-4-yl)indolin-2-one hydrochloride (CAS 1137949-86-0)
- 5-(propan-2-yl)-3-(trifluoromethyl)-1,2-oxazole-4-carboxylic acid (CAS 1697694-79-3)
- 2-(Bromomethyl)-1-methylpyrrolidine (CAS 734470-67-8)
- 1-(3,5-Dimethoxybenzyl)-4-(thiophen-2-yl)piperidine (CAS 1396868-89-5)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
Why CATO?
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