Bictegravir Impurity 7 CAS 1284248-73-2
| CAS No. | 1284248-73-2 |
| Molecular Formula | C5H11NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bictegravir Impurity 7.
Bictegravir Impurity 7 (CAS 1284248-73-2) is a certified pharmaceutical impurity reference standard with the molecular formula C5H11NOHCl and a molecular weight of 137.61 g/mol.
The molecular framework of Bictegravir Impurity 7 (C5H11NOHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H11NO HCl |
| Molecular Weight | 137.61 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bictegravir Standards
- Bictegravir Related Compound 2 (CAS 1110772-05-8)
- Bictegravir Related Compound C001/Dolutegravir Intermediate-1 (CAS 1335210-23-5)
- Bictegravir (CAS 1611493-60-7)
- Bictegravir sodium (CAS 1807988-02-8)
- Bictegravir-15N, d2 (CAS CATO-C4X-21811)
- Bictegravir Impurity 10(2R,5S,13aS) (CAS CATO-C4X-218110)
- Bictegravir impurity 11 (CAS CATO-C4X-218111)
- Bictegravir Impurity 2 (CAS CATO-C4X-21812)
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- Ethyl 5-(4-methoxyphenyl)-1h-pyrazole-4-carboxylate (CAS 936128-48-2)
- (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate (CAS 1469801-67-9)
- 2-Bromo-1-[(4-chlorophenyl)sulfanyl]-4-nitrobenzene (CAS 58291-59-1)
- 2-(N-Methylaminocarbonyl)-3445-pyridineboronic acid pincol ester (CAS 70352-20-4)
- (S)-3-((tert-Butoxycarbonyl)amino)tetrahydrofuran-3-carboxylic acid (CAS 1242457-64-2)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
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