Tucatinib Impurity 21 TFA Salt CAS CATO-C4X-260521
| CAS No. | CATO-C4X-260521 |
| Molecular Formula | C26H26N8O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Tucatinib Impurity 21 TFA Salt is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 612.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Tucatinib Impurity 21 TFA Salt (CAS CATO-C4X-260521) is a certified pharmaceutical impurity reference standard with the molecular formula C26H26N8O3C2HF3O2 and a molecular weight of 612.57 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26N8O3 C2HF3O2 |
| Molecular Weight | 612.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Tucatinib Standards
- Tucatinib Impurity 4 (CAS 1429755-58-7)
- Tucatinib Impurity 44 (CAS 197382-76-6)
- Tucatinib Impurity N6 (CAS 2307628-67-5)
- Tucatinib Impurity N5 (CAS 4706-13-2)
- Tucatinib Impurity 22 (CAS 920966-03-6)
- Tucatinib Impurity 23 (CAS 920966-13-8)
- Tucatinib (CAS 937263-43-9)
- Tucatinib Impurity 1 (CAS CATO-C4X-26051)
Recommended Standards
- Ivacaftor Impurity 6 (CAS 873054-39-8)
- Roxadustat Impurity 131 (CAS CATO-C4X-2213131)
- Pefloxacin Impurity 1 (CAS 81530-83-8)
- 5-(3-Hydroxy-3-methylbut-1-yn-1-yl)nicotinic acid (CAS 886505-83-5)
- 31380-57-1 5-Acetyl-1H-indole-2-carboxylic acid DTXSID40547227 (CAS 31380-57-1)
- Indole-2-carbohydrazide (CAS 5055-39-0)
- 1-(2-(Dimethylamino)ethyl)-3-methyl-1H-pyrazol-5(4H)-one (CAS 143314-24-3)
- (3-Methyl-4-propylphenyl)(thiophen-2-yl)methanol (CAS 1282763-09-0)
- Diethyl 6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-dicarboxylate (CAS 2069184-18-3)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com