Aripiprazole Impurity 3 CAS 129722-34-5
| CAS No. | 129722-34-5 |
| Molecular Formula | C13H16BrNO2 |
| Molecular Weight | 298.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Aripiprazole Impurity 3 (CAS 129722-34-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H16BrNO2 and a molecular weight of 298.18 g/mol.
The molecular framework of Aripiprazole Impurity 3 (C13H16BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Aripiprazole Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16BrNO2 |
| Molecular Weight | 298.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Aripiprazole Standards
- Aripiprazole Impurity 61 (CAS 63309-35-3)
- Aripiprazole Impurity 64 (CAS 63136-84-5)
- Aripiprazole N-Bromobutyl Impurity (CAS 1424857-68-0)
- Aripiprazole Impurity N9 (CAS 870765-38-1)
- Aripiprazole Impurity 71 (CAS CATO-C4X-100871)
- Aripiprazole Impurity 21 (CAS 2250243-33-3)
- Aripiprazole Impurity 48 (CAS 1424857-93-1)
- Aripiprazole-Impurity 10 (CAS 82657-32-7)
Recommended Standards
- tert-Butyl 5-Bromoisoindoline-2-carboxylate (CAS 201940-08-1)
- Tert-butyl (2S,3S)-3-(3-bromophenyl)aziridine-2-carboxylate (CAS 1980008-31-8)
- Tert-butyl (2S,3R)-3-(3-bromophenyl)aziridine-2-carboxylate (CAS 1980008-30-7)
- Zolpidem EP Impurity D (CAS 836627-56-6)
- Baloxavir Impurity 142 (CAS CATO-C4X-2108142)
- Darunavir Impurity 34 (CAS CATO-C4X-160634)
- Nifuratel Impurity 3 (CAS CATO-C4X-12723)
- Tacrolimus impurity 67 (CAS CATO-C4X-130067)
- Methyl 7-(bromomethyl)-2-naphthoate (CAS 1261810-38-1)
- (2S,5S)-1-{2-[(2S,5S)-2,5-Diethylphospholan-1-yl]phenyl}-2,5-diethylphospholane1-oxide (CAS 2635339-89-6)
- n-(Thiazol-5-ylmethyl)butan-1-amine (CAS 1339639-18-7)
- Methyl 4-Methyl-2-oxopentanoate (CAS 3682-43-7)
- 2-(1-(Tert-butoxycarbonyl)-3-(dimethylamino)azetidin-3-yl)acetic acid (CAS 1697298-57-9)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com