Tacrolimus impurity 67 CAS CATO-C4X-130067
| CAS No. | CATO-C4X-130067 |
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tacrolimus impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tacrolimus impurity 67 (CAS CATO-C4X-130067), a pharmacopoeial impurity reference standard (molecular formula C44H69NO12, MW 804.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Tacrolimus impurity 67 (C44H69NO12) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C44H69NO12 |
| Molecular Weight | 804.02 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus (CAS 104987-11-3)
- Tacrolimus Impurity 15 (CAS CATO-C4X-130015)
- Tacrolimus Impurity 17 (CAS CATO-C4X-130017)
- Tacrolimus EP Impurity F (CAS 1393890-33-9)
- Tacrolimus EP Impurity G (CAS 144490-63-1)
- Tacrolimus Impurity 36 (CAS 131944-48-4)
- Tacrolimus Impurity 37 (CAS CATO-C4X-130037)
- Tacrolimus Impurity 38 (CAS CATO-C4X-130038)
Recommended Standards
- Tacrolimus Impurity 57 (CAS CATO-C4X-130057)
- Tacrolimus EP Impurity D (CAS 129212-35-7)
- Tacrolimus Impurity 56 (CAS CATO-C4X-130056)
- Tacrolimus Lactone Isomer (Iso-FK-506) (CAS 134590-88-8)
- Orforglipron Impurity 111 (CAS CATO-C4X-3234111)
- Eltrombopag Impurity 55 (CAS 13636-53-8)
- Paliperidone Impurity 72 (CAS CATO-C4X-172472)
- 5-(2,6-Difluorophenyl)-3-(5-phenyl-2-(1H-pyrrol-1-yl)furan-3-yl)-1,2,4-oxadiazole (CAS 866131-26-2)
- 3-[(4-ethylpiperazin-1-yl)methyl]benzene-1-carboximidamide trihydrochloride (CAS 1235440-83-1)
- 3-Oxazol-5-yl-pyridine (CAS 70380-74-4)
- 2-amino-3H,4H-benzo[g]quinazolin-4-one (CAS 33987-05-2)
- 2-Ethoxy-5-fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2377607-13-9)
- Methyl 3,4-Dihydroxy-2-methylbenzoate (CAS 740799-82-0)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com