Dabigatran Impurity 80 CAS 1307233-94-8
| CAS No. | 1307233-94-8 |
| Molecular Formula | C20H21ClN4O3 |
| Molecular Weight | 400.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Dabigatran Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Dabigatran Impurity 80 (CAS 1307233-94-8, C20H21ClN4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dabigatran Impurity 80 (C20H21ClN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 400.86 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H21ClN4O3 |
| Molecular Weight | 400.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dabigatran Standards
- Dabigatran Impurity 115 (CAS CATO-C4X-1089115)
- Dabigatran Impurity 133 (CAS CATO-C4X-1089133)
- Dabigatran Impurity 127 (CAS 1422435-37-7)
- Dabigatran Impurity 104 (CAS CATO-C4X-1089104)
- Dabigatran Impurity 67 (CAS 429659-01-8)
- Dabigatran Impurity 116 (CAS CATO-C4X-1089116)
- Dabigatran Impurity 27 (CAS 1642853-67-5)
- Dabigatran Impurity 28 (CAS 1456889-80-7)
Recommended Standards
- 10L-751 2-[(5Z)-5-[(4-chlorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione 477845-32-2 (CAS 477845-32-2)
- Melphalan Impurity 28 (CAS CATO-C4X-198828)
- Ethyl 4-[2-(4-Chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperazine-1-carboxylate (CAS 931728-33-5)
- 4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-2-propanoic Acid Methyl Ester (CAS 100827-83-6)
- Tegoprazan Impurity 143 (CAS CATO-C4X-2297143)
- Dapagliflozin Impurity 85 (CAS 2452300-79-5)
- Moxifloxacin Impurity 39 (CAS 151213-40-0)
- 1-(2,6-Dimethylpyrimidin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1342219-83-3)
- 2-Bromo-1-(pyridin-4-yl)propan-1-one (CAS 780692-61-7)
- Methyl (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate (CAS 546115-43-9)
- Baxdrostat Impurity 32 (CAS 1428651-98-2)
- 1-(4-Bromobutoxy)-4-methylbenzene (CAS 3257-49-6)
- Iopamidol Impurity 29 (CAS 2756222-40-7)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com