Netupitant Impurity 24 CAS 1314722-26-3
| CAS No. | 1314722-26-3 |
| Molecular Formula | C12H10F6O2 |
| Molecular Weight | 300.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Netupitant Impurity 24.
Netupitant Impurity 24 (CAS 1314722-26-3) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10F6O2 and a molecular weight of 300.20 g/mol.
Based on its molecular formula C12H10F6O2, Netupitant Impurity 24 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Netupitant Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F6O2 |
| Molecular Weight | 300.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Netupitant Standards
- Netupitant Impurity 25 (CAS 1314651-44-9)
- Netupitant Impurity 44 (CAS CATO-C4X-122344)
- Netupitant Impurity 51 (CAS CATO-C4X-122351)
- Netupitant Impurity 63 (CAS CATO-C4X-122363)
- Netupitant Impurity 16 (CAS 2973069-91-7)
- Netupitant Impurity 17 (CAS CATO-C4X-122317)
- Netupitant Impurity 18 (CAS CATO-C4X-122318)
- Netupitant Impurity 19 (CAS CATO-C4X-122319)
Recommended Standards
- 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid (CAS 289686-70-0)
- Ethane-1,1-diylbis(butylselane) (CAS 26822-79-7)
- 5-(Trifluoromethyl)thiophen-3-yl trifluoromethanesulfonate (CAS 827322-77-0)
- 3-((3,4-Dichlorophenyl)amino)-1-(thiophen-2-yl)propan-1-one (CAS 93523-13-8)
- Epalrestat impurity 48 (CAS CATO-C4X-223648)
- Efinaconazole Impurity 41 (CAS CATO-C4X-124341)
- Safinamide impurity 01 (CAS 1443302-79-1)
- 3,5,6,7-Tetrahydro-2-methyl-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidine-4-thione (CAS 307342-23-0)
- L-DOPA ethyl ester Hydrochloride (CAS 39740-30-2)
- Benzyl Mercaptan (CAS 100-53-8)
- Bilastine impurity 111 (CAS CATO-C4X-2253111)
- 5-Amino-4-iodo-2-methylbenzoic acid (CAS 2092592-62-4)
- Methyl 2-(cyclopent-1-en-1-yl)acetate (CAS 21622-07-1)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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