Netupitant Impurity 16 CAS 2973069-91-7
| CAS No. | 2973069-91-7 |
| Molecular Formula | C17H19ClN2O |
| Molecular Weight | 302.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Netupitant Impurity 16 (CAS 2973069-91-7, C17H19ClN2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Netupitant Impurity 16 (C17H19ClN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 302.80 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Netupitant Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H19ClN2O |
| Molecular Weight | 302.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Netupitant Standards
- Netupitant Impurity 17 (CAS CATO-C4X-122317)
- Netupitant Impurity 18 (CAS CATO-C4X-122318)
- Netupitant Impurity 19 (CAS CATO-C4X-122319)
- Netupitant Impurity 20 (CAS CATO-C4X-122320)
- Netupitant Impurity 21 (CAS CATO-C4X-122321)
- Netupitant Impurity 24 (CAS 1314722-26-3)
- Netupitant Impurity 25 (CAS 1314651-44-9)
- Netupitant Impurity 44 (CAS CATO-C4X-122344)
Recommended Standards
- N-(tert-Butyl)-6-chloro-4-(o-tolyl)nicotinamide (CAS 342417-04-3)
- N-(3-chloro-1-tetrahydropyran-2-yl-pyrazolo[4,3-c]pyridin-6-yl)acetamide (CAS 2708286-43-3)
- N-(3-Amino-4-chlorophenyl)-4-(tert-butyl)benzamide (CAS 926217-29-0)
- methyl 3-chloro-6-methoxy-5H-pyrido[4,3-b]indole-8-carboxylate (CAS 2641336-14-1)
- Rivastigmine Impurity 16 (CAS CATO-C4X-138416)
- Ilaprazole impurity 207 (CAS CATO-C4X-1130207)
- Doxepin EP Impurity D HCl ((Z)-Doxepin HCl) (CAS 25127-31-5)
- 4-(bromomethyl)-3,6-dihydro-2H-pyran (CAS 115198-12-4)
- (but-2-yn-1-yl)[(6-methylpyridin-2-yl)methyl]amine (CAS 1250917-32-8)
- 5-[(4-chloro-1h-pyrazol-1-yl)methyl]furan-2-carboxylic acid (CAS 312309-03-8)
- 5-Borono-2-methylbenzoic acid (CAS 1256346-18-5)
- 2,4-Dimethyl-N-(thiazol-5-ylmethyl)aniline (CAS 1482088-48-1)
- 1-Fluoro-2-(sulfinylamino)benzene (CAS 74653-64-8)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com