Netupitant Impurity 17 CAS CATO-C4X-122317
| CAS No. | CATO-C4X-122317 |
| Molecular Formula | C17H19ClN2O |
| Molecular Weight | 302.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Netupitant Impurity 17 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Netupitant Impurity 17 (CAS CATO-C4X-122317, C17H19ClN2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19ClN2O |
| Molecular Weight | 302.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Netupitant Standards
- Netupitant Impurity 16 (CAS 2973069-91-7)
- Netupitant Impurity 18 (CAS CATO-C4X-122318)
- Netupitant Impurity 19 (CAS CATO-C4X-122319)
- Netupitant Impurity 20 (CAS CATO-C4X-122320)
- Netupitant Impurity 21 (CAS CATO-C4X-122321)
- Netupitant Impurity 24 (CAS 1314722-26-3)
- Netupitant Impurity 25 (CAS 1314651-44-9)
- Netupitant Impurity 44 (CAS CATO-C4X-122344)
Recommended Standards
- N-(tert-Butyl)-6-chloro-4-(o-tolyl)nicotinamide (CAS 342417-04-3)
- N-(3-chloro-1-tetrahydropyran-2-yl-pyrazolo[4,3-c]pyridin-6-yl)acetamide (CAS 2708286-43-3)
- N-(3-Amino-4-chlorophenyl)-4-(tert-butyl)benzamide (CAS 926217-29-0)
- methyl 3-chloro-6-methoxy-5H-pyrido[4,3-b]indole-8-carboxylate (CAS 2641336-14-1)
- Cinepazide Impurity 8 (CAS 39890-45-4)
- Phenacetin Impurity 2 (CAS 65570-13-0)
- Bimatoprost Impurity 17 (Mixture of Diastereomers) (CAS CATO-C4X-196417)
- 2-(5-Bromothiophen-2-yl)-2-methoxyacetic acid (CAS 338745-19-0)
- 6-Chloro-N-methoxy-N-methylpyrazine-2-carboxamide (CAS 1223444-91-4)
- 6-Bromo-4-phenylquinazoline-2-carboxylic acid (CAS 1416440-16-8)
- 1-(2,4-Dichlorobenzyl)-4-nitro-1h-pyrazole (CAS 90723-90-3)
- 5-methoxy-1-prop-2-ynyl-benzimidazole (CAS 2735014-64-7)
- 3-Amino-N-cyclopropyl-4-fluorobenzene-1-sulfonamide (CAS 639859-24-8)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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