Netupitant Impurity 44 CAS CATO-C4X-122344
| CAS No. | CATO-C4X-122344 |
| Molecular Formula | C12H10F6O2 |
| Molecular Weight | 300.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Netupitant Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Netupitant Impurity 44 (CAS CATO-C4X-122344) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10F6O2 and a molecular weight of 300.20 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Netupitant Impurity 44 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 300.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H10F6O2 |
| Molecular Weight | 300.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Netupitant Standards
- Netupitant Impurity 24 (CAS 1314722-26-3)
- Netupitant Impurity 25 (CAS 1314651-44-9)
- Netupitant Impurity 51 (CAS CATO-C4X-122351)
- Netupitant Impurity 63 (CAS CATO-C4X-122363)
- Netupitant Impurity 16 (CAS 2973069-91-7)
- Netupitant Impurity 17 (CAS CATO-C4X-122317)
- Netupitant Impurity 18 (CAS CATO-C4X-122318)
- Netupitant Impurity 19 (CAS CATO-C4X-122319)
Recommended Standards
- 2-(3,5-Bis(trifluoromethyl)phenyl)-2-methylpropanoic acid (CAS 289686-70-0)
- Abemaciclib Impurity 50 (CAS CATO-C4X-293750)
- Ethane-1,1-diylbis(butylselane) (CAS 26822-79-7)
- 2-((2,4-Dichlorobenzyl)thio)-6-methylpyrimidin-4-amine (CAS 1036191-90-8)
- Diquafosol Impurity 6 (CAS CATO-C4X-21496)
- Iobitridol Impurity 14 (CAS CATO-C4X-317814)
- Bosentan Impurity (CAS 253688-61-8)
- N,N-Diphenyl-[2,2':5',2''-terthiophen]-5-amine (CAS 888488-90-2)
- Ethyl 3-cyano-3-ethyl-5-methylhexanoate (CAS 90355-26-3)
- 8-Methyl-N-(4-(trifluoromethoxy)phenyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide (CAS 477887-29-9)
- N-{2-[4-(2-chloropropanoyl)phenyl]ethyl}acetamide (CAS 105842-89-5)
- 2-Methyl-5-nitrobenzenesulfinic acid (CAS 732223-56-2)
- Oxazole, 2,2′-(2,3-naphthalenediyl)bis[4,5-dihydro-4-(1-methylethyl)-, (4S,4′S)- (CAS 591754-02-8)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
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